Xuechang Zhou

[CV download]

Ph.D. in chemistry, CUHK, 2010 (expected)

Mphil. in chemistry, CUHK, 2007

B.S. in polymer chemistry, USTC, 2005

 

Address:  

Room G05/07, CSLB, CUHK, Shatin, N.T.,

Hong Kong.

Office:    (852) 26096254

Mobile:   (852) 97472708

Email:    xuechangzhou@cuhk.edu.hk

http://ihome.cuhk.edu.hk/~s0704924/

Biography:

 

I entered the University of Science and Technology of China (USTC) in 2001 and received my B.S. in polymer chemistry in 2005. I started my research at an early stage when I was a sophomore. During this period, under the supervision of Prof. Guangzhao Zhang, I earned two honors for my research and the research results were published by Macromolecules and Journal of Physical Chemistry B.. These experiences greatly stimulated my research interests and I made my career goal on research.

 

In the fall of 2005, I was admitted into The Chinese University of Hong Kong (CUHK), pursuing my postgraduate life under the guidance of Prof. Bo Zheng in department of chemistry. As a full time graduate student, I cherished the chance to focus directly on the research—microfluidics, an emerging and interdisciplinary field. Under the supervision of Prof. B. Zheng, I developed several microfluidic systems, including microwell-based system for high-throughput screening of protein crystallization conditions, controlled microevaporation microfluidic system for constructing the phase diagram of polymer solutions, and the degassed PDMS nanoliter liquid dispensing system. The research results were published by Analytical Chemistry, Macromolecular Rapid Communications, MicroTAS conference, and filed one US provisional patent.

 

My current research interest is the exploration of the miniaturization of the traditional bioanalytical method, utilizing novel microfluidic technologies to manipulating biological samples (including oligonucleotide, proteins, cells, and tissues) to perform reactions and bioassay.

 

Research Interests:

 

1.

Bioanalytical applications of microfluidics

 

2.

Droplet/microwell-based microfluidics

 

3.

Surface patterning and multiplexed bioassay

Selected Publications:

 

1.

© 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Constructing the Phase Diagram of an Aqueous Solution of Poly(N-isopropyl acrylamide) by Controlled Microevaporation in a Nanoliter Microchamber

 

Xuechang Zhou; Junfang Li; Chi Wu; Bo Zheng*.

Macromolecular Rapid Communications 2008, 29.1363.

[Abstract] [Full text in PDF] [Selected as the back cover] [Materials Views August 2008] [Impact factor: 3.907, times cited: 3, ranking # 9 in total citations and # 7 in ISI impact factor in the polymer science category.]

 

 

2.

© 2007 American Chemical Society

 

Nanoliter Dispensing Method by Degassed Poly(dimethylsiloxane) Microchannels and Its Application in Protein Crystallization

 

Xuechang Zhou; Lana Lau; Wendy Wai Ling Lam; Shannon Wing Ngor Au; Bo Zheng*.

Analytical Chemistry 2007, 79, 4942.

[Abstract] [Full text in PDF] [Impact factor: 5.712, times cited: 9, ranking #1 both in ISI impact factor and total citations in the analytical chemistry category]

 

 

 

3.

© 2007 American Chemical Society

 

Thermoresponsive Triblock Copolymer Aggregates Investigated by Laser Light Scattering

 

Xuechang Zhou; Xiaodong Ye; Guangzhao Zhang*.

Journal of Physical Chemistry B. 2007, 111, 5111.

[Abstract] [Full text in PDF] [Impact factor: 4.189, times cited: 10, ranking #1 in total citations and #22 in ISI impact factor in the physical chemistry category]

 

 

 

4.

A Microfluidic Dispensing System for Screening Protein Crystallization Conditions

Xuechang Zhou; Bo Zheng*,

MicroTAS 2007, 1393.

 

5.

Systems and Methods for Performing Screening and Assaying

Bo Zheng*; Xuechang Zhou,

US Provisional Patent, filed 2006 Nov. 13.

 

6.

Adsorption of Polymeric Micelles and Vesicles on a Surface Investigated by Quartz Crystal Microbalance

Yunfeng Yan; Xuechang Zhou; Jing Ji; Lifeng Yan; Guangzhao Zhang*,

Journal of Physical Chemistry B. 2006, 110, 21055.

[Abstract] [Full text in PDF]

[Impact factor: 4.189, times cited: 6, ranking #1 in total citations and #22 in ISI impact factor in the physical chemistry category]

 

7.

Conformational Transition of Tethered Poly(N-isopropylacrylamide) Chains in Coronas of Micelles and Vesicles

Weian Zhang; Xuechang Zhou; Hao li; Yuee Fang; Guangzhao Zhang*,

[Abstract] [Full text in PDF]

Macromolecules 2005, 38, 909. [Impact factor: 4.407, times cited: 41, ranking 1# in total citations and 5# in ISI impact factor in the polymer science category]

 

Conference Presentations:

 

1.         Xuechang Zhou; Bo Zheng*, “Constructing the Phase Diagram of Polymer Aqueous solution in Nanoliter Volume” The 15th Symposium on Chemistry Postgraduate Research in Hong Kong, 28 April 2008, Hong Kong

 

2.         Xuechang Zhou; Bo Zheng*, “A Microfluidic Dispensing System for Screening Protein Crystallization Conditions”, The 7th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 7-11 October 2007, Paris, France.

 

3.         Xuechang Zhou; Bo Zheng*, “A Microfluidic Dispensing System for Screening of Protein Crystallization Conditions”, The 3rd SBE International Conference on Bioengineering and Nanotechnology (ICBN), 12-15 August, 2007, Biopolis, Singapore

 

4.         Xuechang Zhou; Bo Zheng*, “A Nanoliter Liquid Dispensing Method and Its Application in Screening of Protein Crystallization conditions” The 14th Symposium on Chemistry Postgraduate Research in Hong Kong, 28 April 2007, Hong Kong [Best Poster Award]

 

5.         Xuechang Zhou; Lana Lau; Bo Zheng*,“High-throughput Screening of Conditions of Protein Crystallization in Nanoliter Volumes” The 13th Symposium on Chemistry Postgraduate Research in Hong Kong, 22 April 2006, Hong Kong

 

 

 

 

 

 

 

Last updated: 22 September 2009

 

Copyright © 2009 Xuechang Zhou