Personal Home Page of CHU, Yiu-Wai

· Part-time Lecturer, Master of Science Programme in Medical Laboratory Sciences, Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, HKSAR, China

· Project Manager, C K Life Sciences International, Inc.

· Research Officer & Postdoctoral Research Fellow, Department of Microbiology, The Chinese University of Hong Kong, HKSAR, China

· Visiting Scientist, Antimicrobial Research Group, University of Birmingham, UK

· Part-time Tutor, Department of Science and Technology, The Open University of Hong Kong, HKSAR, China

· Visiting Scientist, Laboratory of HealthCare Associated Infection, Health Protection Agency, London, UK

· Postdoctoral Researcher, School of Life Sciences, University of Westminster, London, UK

Peer-reviewed Publications

· Chu, YW^*, VWN Tung, TKM Cheung, MY Chu, N Cheng, C Lai, DNC Tsang & JYC Lo. (2011) Carbapenemases in enterobacteria in Hong Kong, China, 2009. Emerging Infectious Diseases. 17:130-132.

· Chan, J^*, YW Chu, MY Chu, TKM Cheung & JYC Lo. (2009) Epidemiological Analysis of Streptococcus pyogenes infections in Hong Kong. Pathology. 41:681-686. Related articles.

· Chu, YW^*, TKM Cheung, MY Chu, JYC Lo & L Dijkshoorn. (2009) OXA-23-type imipenem resistance in Acinetobacter baumannii in Hong Kong. International Journal of Antimicrobial Agents. 34:285-286. Related articles.

· Chu, YW^*, CH Wong, MY Chu, CPF Cheung, TKM Cheung, C Tse, WK Luk & JYC Lo. (2009) Varibaculum cambriense infections in Hong Kong, China, 2006. Emerging Infectious Diseases. 15:1137-1139.

· Chu, YW^*, TKM Cheung, MY Chu, VYM Tsang, JTL Fung, KM Kam & JYC Lo. (2009) Resistance to tetracycline, erythromycin and clindamycin in Streptococcus suis serotype 2 in Hong Kong. International Journal of Antimicrobial Agents. 34:181-182. Related articles.

· Zarrilli, R^*, M Giannouli, A Di Popolo, YW Chu, M Vaneechoutte, L Dijkshoorn & TC Chang. (2009) Identification of Acinetobacter Genomic Species 13TU by Sequence Analysis of the 16S-23S rRNA Gene Spacer Region. Journal of Clinical Microbiology. 47:1281-1282. Related articles.

· Cheung TKM, YW Chu, MY Chu, VYM Tsang & JYC Lo^*. (2008) Panton-Valentine leucocidin-positive meticillin-resistant Staphylococcus aureus in the community in Hong Kong. Journal of Medical Microbiology. 57:1440-1443. Related articles.

· Chu, YW^*, TKM Cheung, CH Wong, GKL Tsang, K Lee, SSY Lau & KM Kam. (2008) Quinolone resistance and correlation to other antimicrobial resistances in faecal isolates of Escherichia coli in Hong Kong. Chemotherapy. 54:274-278. Related articles.

· Chu, YW^*, AKF Chan, GKL Tsang & JYC Lo. (2007) Detection of cysteine-dependent Escherichia coli (CDEC) in a public health laboratory setting in Hong Kong. Journal of Medical Microbiology. 56:1704. Related articles.

· Chu, YW^*, C Tse, GKL Tsang, DKS So, JTL Fung & JYC Lo. (2007) Invasive group B Streptococcus isolates showing reduced susceptibility to penicillin in Hong Kong. Journal of Antimicrobial Chemotherapy. 60:1407-1409. Related articles.

· Chu, YW^*, GKL Tsang, CH Wong, MSW Kwok, RKO Wong, JYC Lo & KM Kam. (2007) Authors' reply to 'Controversial data on the association of Aeromonas with diarrhoea in a recent Hong Kong study'. Journal of Medical Microbiology. 56:998. Related articles.

· Chu, YW^*, TKM Cheung, V Tung, F Tiu, J Lo, R Lam, R Lai & KK Wong. (2007) A blood isolate of Neisseria meningitidis showing reduced susceptibility to quinolones in Hong Kong. International Journal of Antimicrobial Agents. 30:94-95. Related articles.

· Luey, CKY, YW Chu, TKM Cheung, CCP Law, MY Chu, DTL Cheung & KM Kam^*. (2007) Rapid pulsed-field gel electrophoresis protocol for subtyping of Streptococcus suis serotype 2. Journal of Microbiological Methods. 68:648-50. Related articles.

· Chu, YW^*, TKM Cheung, TK Ng, D Tsang, WK To, KM Kam & JYC Lo. (2006) Quinolone resistance determinant qnrA3 in clinical isolates of Salmonella in 2000-2005 in Hong Kong. Journal of Antimicrobial Chemotherapy. 58:904-905. Related articles.

· Chu, YW^*, SL Chau & ETS Houang. (2006) Presence of active efflux systems AdeABC, AdeDE and AdeXYZ in different Acinetobacter genomic DNA groups. Journal of Medical Microbiology. Journal of Medical Microbiology. 55:477-478. Related articles.

· Chu, YW^*, GKL Tsang, CH Wong, MSW Kwok, RKO Wong, JYC Lo & KM Kam. (2006) Lack of association between presentation of diarrhoeal symptoms and faecal isolation of Aeromonas app. amongst out-patients in Hong Kong. Journal of Medical Microbiology. 55:349-351. Related articles.

· Chu, YW^*, TKM Cheung, JYW Ngan & KM Kam. (2005) EDTA susceptibility leading to false detection of metallo-beta-lactamase in Pseudomonas aeruginosa by Etest and an imipenem-EDTA disk method. International Journal of Antimicrobial Agents. 26:340-341. Related articles.

· Cheung, TKM, YW Chu^*, MY Chu, CH Ma, RWH Yung & KM Kam. (2005) Plasmid-mediated resistance to ciprofloxacin and cefotaxime in clinical isolates of Salmonella enterica serotype Enteritidis in Hong Kong. Journal of Antimicrobial Chemotherapy. 56:586-589. Related articles. Cited by.

· Cheung, TKM, YW Chu^*, GKL Tsang, JYW Ngan, ISC Hui & KM Kam. (2005) Emergence of CTX-M-type beta-lactam resistance in Shigella spp. in Hong Kong. International Journal of Antimicrobial Agents. 25:350-352. Related articles.

· Chau, SL, YW Chu^* & ETS Houang. (2004) Novel Resistance-Nodulation-Cell Division Efflux System AdeDE in Acinetobacter Genomic DNA Group 3. Antimicrobial Agents and Chemotherapy. 48:4054-4055. Related articles. Cited by.

· Chu, YW^*, MY Chu, KY Luey, YW Ngan, KL Tsang & KM Kam. (2004) Genetic relatedness and quinolone resistance of Campylobacter jejuni strains isolated in 2002 in Hong Kong. Journal of Clinical Microbiology 42:3321-3323. Related articles. Cited by.

· Houang, ETS^*, YW Chu, WS Lo, KY Chu & AFB Cheng. (2003) Epidemiology of rifampin ADP-ribosyltransferase (arr-2) and the metallo-beta-lactamase (bla_IMP-4) gene cassettes in new class 1 integrons in Acinetobacter strains isolated from blood cultures 1997 to 2000. Antimicrobial Agents and Chemotherapy 47:1382-1390. Related articles. Cited by.

· Houang, ETS^*, YW Chu, KY Chu, KC Ng, CM Leung & AFB Cheng. (2003) Significance of genomic DNA Group delineation in comparative studies of antimicrobial susceptibility of Acinetobacter spp. Antimicrobial Agents and Chemotherapy 47:1472-1475. Related articles. Cited by.

· Booton, GC^*, DJ Kelly, YW Chu, DV Seal, E Houang, DSC Lam, TJ Byers & PA Fuerst. (2002) 18S ribosomal DNA typing and tracking of Acanthamoeba species isolates from corneal scrape specimens, contact lenses, lens cases, and home water supplies of Acanthamoeba keratitis patients in Hong Kong. Journal of Clinical Microbiology 40:1621-1625. Related articles. Cited by.

· Chu, YW, M Afzal-Shah, ETS Houang^*, M-F Palepou, DJ Lyon, N Woodford & DM Livermore. (2001) IMP-4, a novel metallo-beta-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998. Antimicrobial Agents and Chemotherapy 45:710-714. Related articles. Cited by.

· Houang, ETS^*, YW Chu, CM Leung, KY Chu, J Berlau, KC Ng & AFB Cheng. (2001) Epidemiology and infection control implications of Acinetobacter spp. in Hong Kong. Journal of Clinical Microbiology 39:228-234. Related articles. Cited by.

· Chu, YW, CM Leung, ETS Houang^*, KC Ng, CB Leung, HY Leung & AFB Cheng. (1999) Skin carriage of acinetobacters in Hong Kong. Journal of Clinical Microbiology 37:2962-2967. Related articles. Cited by.

· Chu, YW, ETS Houang^* & AFB Cheng. (1998) Novel combination of mutations in the DNA gyrase and topoisomerase IV genes in laboratory-grown fluoroquinolone-resistant Shigella flexneri mutants. Antimicrobial Agents and Chemotherapy 41:3051-3052. Related articles. Cited by.

· Houang, ETS^*, YW Chu, TKC Ng & AFB Cheng. (1998) Study of the relatedness of isolates of Shigella flexneri and Shigella sonnei obtained in 1986 and 1987 and in 1994 and 1995 from Hong Kong. Journal of Clinical Microbiology 36:2404-2407. Related articles. Cited by.

· Chu, YW, ETS Houang^*, DJ Lyon, JM Ling, TK Ng & AFB Cheng. (1998) Antimicrobial resistance in Shigella flexneri and Shigella sonnei in Hong Kong, 1986 to 1995. Antimicrobial Agents and Chemotherapy 42:440-443. Related articles. Cited by.

· Chu, YW, D Renno & G Saunders^*. (1997) Extracellular pH affects regulation of the pcbAB gene in Penicillium chrysogenum. Applied Microbiology and Biotechnology 47:250-254. Related articles.

· Vichitsoonthonkul, T, YW Chu, V Patel, R Patel & G Saunders^*. (1996) Factors affecting DNA binding proteins and pcbC transcription levels in Penicillium chrysogenum. Current Genetics 30:447-454. Related articles.

· Chu, YW, D Renno & G Saunders^*. (1995) Detection of a protein which binds specifically to the upstream region of the pcbAB gene in Penicillium chrysogenum. Current Genetics 27:184-189. Related articles.

^*corresponding author

Large Scale Collaborative Study

· Kam, KM^*, CK Luey, MB Parsons, KL Cooper, GB Nair, M Alam, MA Islam, DT Cheung, YW Chu, T Ramamurthy, GP Pazhani, SK Bhattacharya, H Watanabe, J Terajima, E Arakawa, OA Ratchtrachenchai, S Huttayananont, EM Ribot, P Gerner-Smidt, B Swaminathan; Vibrio parahaemolyticus PulseNet PFGE Protocol Working Group. (2008) Evaluation and validation of a PulseNet standardized pulsed-field gel electrophoresis protocol for subtyping Vibrio parahaemolyticus: an international multicenter collaborative study. Journal of Clinical Microbiology. 46:2766-2773. Cited by.

Conference Abstracts

· Luey, CKY, YW Chu, DTL Cheung, TKM Cheung, CPY Law, MY Chu, DTL Cheung & KM Kam (2007) Rapid pulsed-field gel electrophoresis protocol for subtyping of Streptococcus suis. Eleventh Annual PulseNet Update Meeting 2007, Providence, Rhode Island, USA. April 2007.

· Chu, YW, CKY Luey, DTL Cheung, MY Chu, AWH Chiu, SFS Leung, CH Ma & KM Kam on behalf of all the participants of PulseNet Asia Pacific (2005) Present State of Development of PulseNet Asia Pacific, 2005. Nineth Annual PulseNet Update Meeting 2005, Seattle, Washington, USA. May 2005.

· Houang, ETS, KM Kam, SL Chau & YW Chu. (2003) Penicillin-Binding Protein 2 and reduced cefixime susceptibility in Neisseria gonorrhoeae in Hong Kong. International Society of Sexually Transmitted Disease Research Congress, Ottawa, Canada. July 2003.

· Houang, ETS, CM Leung, KY Chu, YW Chu, KC Ng & AFB Cheng. (2002) Acinetobacter spp from food and its significance in hospital-acquired infections in Hong Kong. Annual meeting of the Society of Healthcare Epidemiology of America, Salt Lake City, Utah, USA. April 2002.

· Houang, ETS, YW Chu, WS Lo, SL Chau, KY Chu & AFB Cheng. (2001) A new Class 1 integron bearing the 6'-Ib aminoglycoside acetyltransferase (aacA4) and rifampicin ADP-ribosylating transferase (arr-3) genes in Acinetobacter. Forty-first Interscience Conference in Antimicrobial Agents and Chemotherapy, Chicago, USA. September 2001.

· Houang, ETS, J Berlau, YW Chu, KC Ng & TL Pitt. (2001) Susceptibility of Acinetobacter genomic species to free fatty acids of the skin. American Society of Microbiology General meeting, Orlando, USA. May 20-24, 2001.

· Houang, ETS, KY Chu, CM Leung, YW Chu & AFB Cheng. (2001) Distribution of acinetobacters in the environment in Hong Kong. Fifth Annual Scientific meeting - The Hong Kong Society for Infectious Diseases, Hong Kong SAR, China, March 2001.

· Houang ET, YW Chu, NWS Lo, CKY Chu & AFB Cheng. (2001) Integron-mediated rifampicin resistance and IMP-4 in acinetobacters from blood cultures in Hong Kong. Third International Symposium on Antimicrobial Agents & Resistance, Seoul, Korea, April 2001.

· Chu, YW, ETS Houang, NWS Lo, AFB Cheng, LJV Piddock & D Livermore. (2000) Epidemiology of carbapenem resistant acinetobacters from blood cultures in Hong Kong in 1997-98. Fortieth Interscience Conference in Antimicrobial Agents and Chemotherapy, Toronto, Canada, September 2000.

· Chu, CKY, TJK Van der Reijden, YW Chu, ETS Houang, AFB Cheng & L Dijkshoorn. (2000) The use of amplified fragment length polymorphism (AFLP) analysis for the determination of genomic DNA group of acinetobacters unclassifiable by amplified rDNA restriction analysis (ARDRA). Fifth International Meeting on Bacteriological Epidemiological Markers, Noordwijkerhout, The Netherlands.

· Houang, ETS, YW Chu, CM Leung, KY Chu, J Berlau, KC Ng & AFB Cheng. (2000) Acinetobacter spp. in Hong Kong: epidemiology and infection control implications. Fifth International Symposium on the Biology of Acinetobacter, Noordwijkerhout, The Netherlands.

· Houang, ETS, CKY Chu, NWS Lo, YW Chu & AFB Cheng. (2000) The clinically important Acinetobacter genomic DNA groups have different ability for glass adherence: a possible marker in the pathogenesis of ventilator-associated pneumonia. Biofilms 2000, Big Sky, Montana, USA. no.184.

· Chu, YW, M Afzal-Shah, ETS Houang, M-F Palepou, DJ Lyon, N Woodford & DM Livermore. (2000) Carbapenem-resistant Acinetobacter spp with IMP-3, a new zinc beta-lactamase in Hong Kong. Tenth European Congress of Clinical Microbiology and Infectious Diseases, Stockholm, Sweden. MoP173.

· Houang, ETS, YW Chu, TKC Ng, AFB Cheng & LJV Piddock. (1998) Typing and mechanism(s) of resistance of 23 ciprofloxacin-resistant Acinetobacter baumannii isolates from 8 patients from Hong Kong. Thirty-eighth Interscience Conference in Antimicrobial Agents and Chemotherapy, San Diego USA, September 1998.

· Houang, ETS, YW Chu & AFB Cheng. (1997) Clonal relatedness of Shigella flexneri and Shigella sonnei isolates in Hong Kong 1986-1995. Fourth International Meeting on Bacteriological Epidemiological Markers, Elsinore, Denmark. S401.

· Chu, YW, ETS Houang, JM Ling, DJ Lyon, TK Ng & AFB Cheng. (1997) Antimicrobial resistance of Shigella flexneri and Shigella sonnei in Hong Kong 1986-1995. Eighth European Congress of Clinical Microbiology and Infectious Diseases, Lausanne, Switzerland. P745.

· Chu, YW, D Renno & G Saunders. (1995) Detection of a protein which binds specifically to the upstream region of the pcbAB gene in Penicillium chrysogenum. Eighteenth Fungal Genetics Conference, Monterey, USA. P60.

· Chu, YW, T Vichitsoonthonkul, T Keshavarz, D Renno & G Saunders. (1995) Molecular genetics as a tool to study the physiology of Penicillium chrysogenum grown in fermenters. Symposium of the 1995 IChemE research event / first European conference, Edinburgh, UK. 2:1058-1060.

· Chu, YW, T Vichitsoonthonkul, T Keshavarz, D Renno & G Saunders. (1994) Molecular genetic studies related to the biosynthesis of penicillin. Seventh International Symposium on the Genetics of Industrial Microorganisms, Montreal, Canada. p99.

Oral Presentation

· Cheng, AFB, YW Chu & ETS Houang. (1997) Evaluation of 12 PCR methods for typing of Shigella spp. Fourth International Meeting on Bacterial Epidemiological Markers, Elsinore, Denmark. S801.

Book Chapter

· Vichitsoonthonkul, T, YW Chu, H Sodhi & G Saunders. (1994) Beta-lactam antibiotics produced by genetically engineered filamentous fungi. In: Murooka Y, Imanaka T (eds) Bioprocess Technology Volume 19: Recombinant Microbes for Industrial and Agricultural Applications, Marcel Dekker, New York pp 119-135. Related articles