My Publications

(* in reverse chronological order)
Journal Articles
Book Chapter
Online Publications
Other publication
Selected Conference Publications

Journal Articles (Total 27; 15 as first author)

  1. Fan BJ, Leung YF, Pang CP, Wang DY, Tong WC, Tam POS, Chua JKH, Lau TC, Lam DSC. Polymorphisms in the MYOC promoter unrelated to the risk and severity of primary open angle glaucoma. J Glaucoma. 2004 Oct;13(5):377-84. [PubMed]
  2. Fan BJ, Leung YF, Wang N, Lam SC, Liu Y, Tam OS, Pang CP. Genetic and environmental risk factors for primary open-angle glaucoma. Chin Med J (Engl). 2004 May;117(5):706-10. [PubMed]
  3. Fan BJ, Leung YF, Pang CP, Baum L, Tam OS, Wang N, Lam DSC. Single nucleotide polymorphism of the myocilin gene in primary open-angle glaucoma patients. Chin J Med Genet. 2004 Feb;21(1):70-3. [PubMed]
  4. Leung YF, Cavalieri D. Fundamentals of cDNA microarray analysis. Trends Genet. 2003 Nov; 19: 649-659. [PubMed]
  5. Leung YF, Tam PO, Lee WS, Lam DS, Yam HF, Fan BJ, Tham CC, Chua JK, Pang CP. The dual role of dexamethasone on anti-inflammation and outflow resistance demonstrated in cultured human trabecular meshwork cells. Mol Vis. 2003 Sep 5;9:425-39. [PubMed]
  6. Leung YF, Fan BJ, Lam DSC, Lee WS, Tam POS, Chua JKH, Tham CCY, Lai JSM, Fan DSP, Pang CP. Different Optineurin Mutation Pattern in Chinese Primary Open Angle Glaucoma Patients. Invest Ophthalmol Vis Sci. 2003 Sep;44(9):3880-4. [PubMed]
  7. Fan BJ, Leung YF. Beginning microarray analysis for biologists. J Cell Sci. 2003; 116: 1649-1650 [PubMed]
  8. Lam DSC, Lee WS, Leung YF, Tam POS, Fan DSP, Fan BJ, Pang CP. TGFB-induced factor (TGIF) - a candidate gene for high myopia. Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1012-5. [PubMed]
  9. Lam DSC, Tam POS, Fan DSP, Baum L, Leung YF, Pang CP. Familial high myopia linkage to chromosome 18p. Ophthalmologica. 2003 Mar-Apr;217(2):115-8. [PubMed]
  10. Pang CP, Leung YF, Fan BJ, Baum L, Tong WC, Lee WS, Chua JKH, Fan DSP, Liu Y, Lam DSC. TIGR/MYOC Gene Sequence Alterations in Individuals with and without Primary Open Angle Glaucoma. Invest Ophthalmol Vis Sci. 2002 Oct; 43:3231-3235. [PubMed]
  11. Leung YF, Pang CP. Eye on bioinformatics - dissecting complex disease trait in silico. Applied Bioinformatics. 2002; 1:69-80. [PubMed]
  12. Leung YF. Unravel the mystery of microarray data analysis. Trends Biotechnol. 2002 Sep;20:366-368. [PubMed]
  13. Leung YF. Microarray data analysis for dummies... and experts too? Trends Biochem Sci. 2002 Aug; 27:433-434. [PubMed]
  14. Wang N, Peng Z, Fan B, Liu Y, Dong X, Leung YF, Luan J. Case control study on the risk factors of primary open angle glaucoma in China. Chin J Epidemiol. 2002 Aug;23(4):293-6. [PubMed]
  15. Fan BJ, Leung YF, Pang CP, Dong XM, Liu Y, Luan J, Wang N. Study on single nucleotide polymorphism of TIGR gene in primary open-angle glaucoma patients.  Natl Med J China. 2002 Jun 10; 82: 743-747 [PubMed]
  16. Leung YF, Lam DSC, Pang CP. When drug development meets genomics. Pharmacogenomics J. 2001; 1:237-238. [PubMed]
  17. Leung YF, Pang CP. Trends in proteomics. Trends Biotechnol. 2001; 19:480-482. [PubMed]
  18. Leung YF, Pang CP. All aboard the chip! Trends Biotechnol. 2001; 10:430-431 [PubMed]
  19. Leung YF, Lam DSC, Pang CP. In silico biology: observation, modeling, hypothesis and verification.  Trends Genet. 2001; 17:622-623 [PubMed]
  20. Leung YF, Lam DSC, Pang CP. The miracle of microarray data analysis. Genome Biol. 2001; 2: 4021.1-4021.2. [PubMed][pdf]
  21. Leung YF, Tam POS, Tong WC, Choy KW, Lam DSC, Pang CP. High throughput conformation sensitive gel electrophoresis (HTCSGE) for rapid detection of novel single nucleotide polymorphisms (SNPs). Biotechniques. 2001; 30:334-340  [PubMed]
  22. Leung YF, Tam POS, Baum L, Lam DSC, Pang CP. TIGR proximal promoter GT-repeat polymorphism not associated with myopia. Hum Mutat 2000; 16:533 [PubMed]
  23. Leung YF, Baum L, Lam DSC, Fan DSP, Chua JKH, Pang CP. Absence of trabecular meshwork inducible stretch response (TISR)/ oculomedin gene and proximal promoter mutation in primary open angle glaucoma patients. Hum Genet. 2000; 107:404-5. [PubMed]
  24. Leung YF, Tam POS, Baum L, Chan WM, Lam DSC, Pang CP. Cost Savings Using Automated DNA Sequencing. Biotechniques. 2000; 29:544. [PubMed]
  25. Lam DSC, Leung YF, Chua JKH, Baum L, Fan DS, Choy KW, Pang CP. Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 2000; 41:1386-91. [PubMed]
  26. Pang CP, Leung YF, Chua JKH, Baum L, Fan DSP, Lam DSC. Novel TIGR sequence alteration Val53Ala. Hum Mutat 2000;15:122. [PubMed]
  27. Baum L, Pang CP, Fan DSP, Poon PMK, Leung YF, Chua JKH, Lam DSC. Run-on mutation and three novel nonsense mutations identified in the PAX6 gene in patients with aniridia. Hum Mutat 1999; 14:231-2. [PubMed]

Book Chapter

  1. Leung YF, Pang CP, Lam DSC. Microarray software review. In: A practical approach to microarray data analysis. D.P. Berrar, W. Dubitzky and M. Granzow, (Eds.), Kluwer academic, 2002. 

Online publication

  1. Leung YF. The Essence of Interdisciplinary Research--Mindset Matters. Science. 2003  [http://nextwave.sciencemag.org/cgi/content/full/2003/01/30/4]
  2. Leung YF, Pang CP, Browne K. Guide to microarray hardware - a researcher perspective. Lab-on-a-chip.com 2001. [link to article]

Other publication

  1. [CHINESE] 梁旭輝. 冠病毒專利,人類共有財產. 明報. 2003 Jun 2. [link to article] (This is an article published in a renowned Hong Kong Chinese newspaper called MingPao. The article discusses the potential problems on patenting coronavirus and the effects on SARS research. It also advocates an open access to the raw genome sequence of coronvirus.)

Selected Conference Publications (Total: 46, 14 as first author)

  1. Cavalieri D, De Filippo C, Regev A, Morneau K, Leung YF. Systems Biology And Yeast Comparative and Functional Genomics - Understanding The Mechanism Of Yeast Evolution And Variation And The Epic Quest To Decipher Complex Biological Systems. The First International Symposium on Systems Biology of Yeast. ICSB 2003 - 4th International Conference on Systems Biology. St Louis, USA. 9 November, 2003
  2. Leung YF, Tam POS, Yam GHF, Lee WS, Lam DSC, Fan DSP, Pang CP. Dexamethaxone effects on differential gene expression of an established ocular cell line by NEN micromax cDNA microarray. XXIXth International Congress of Ophthalmology. Sydney, Australia. 21-25 April 2002.
  3. Pang CP, Leung YF. Micro-array based mutational analysis: Genetic basis for predisposition and resistance to disease. 10th International Congress on Infectious Diseases. Singapore March 11-14, 2002. Abstracts 126; 48.002.
  4. Leung YF, Tam POS, Yam GHF, Lee WS, Lam DSC, Fan DSP, Pang CP. Dexamethaxone effects on gene expression of trabecular meshwork cells - Statistical inference of differential gene expression on replicated microarray data by Bayesian method. Pac Symp Biocomput. Hawaii, USA. 3-7 January 2002.
  5. Leung YF, Tam POS, Yam GHF, Lee WS, Lam DSC, Fan DSP, Pang CP. Analysis of Dexamethaxone effect on differential gene expression of an established ocular cell line by NEN MicroMax cDNA microarray. First Singapore Eye Research Institute International Meeting. Singapore. 27-29 September 2001.
  6. Leung YF, Tam POS, Yam GHF, Lee WS, Lam DSC, Fan DSP, Pang CP. Dexamethasone effects on expression profile of cultured trabecular meshwork cells. Beyond Genome 2001. San Francisco, USA. 17-22 June 2001.
  7. Leung YF, Tam POS, Tong WC, Baum L, Choi KW, Lam DSC, Pang CP. HTCSGE: A potential platform for developing microchip analysis of SNPs. Eighth Annual HTT EXPO Advancing Drug Development. Philadelphia, USA. 11-13 June 2001.
  8. Tam POS, Leung YF, Lee WS, Lam DSC, Pang CP. Linear amplification of RNA population from a small number of ocular cells for expression profiling. Microarrays and Microchips Japan. Tokyo, Japan. 4-5 June 2001.
  9. Leung YF, Tam POS, Yam GHF, Lee WS, Lam DSC, Fan DSP, Pang CP. Analysis of Dexamethaxone effect on differential gene expression of an established ocular cell line by NEN MicroMax cDNA microarray. Microarrays and Microchips Japan. Tokyo, Japan. 4-5 June 2001.
  10. Lam DSC, Leung YF, Chua JKH, Fan BJ, Baum L, Pang CP. TIGR/MYOC may not be necessary for normal eye function. Invest Ophthalmol Vis Sci 2001;41 (ARVO Suppl):S563-3023.
  11. Lee WS, Leung YF, Tang HM, Fan DSP, Lau TC, Pang CP. alpha-A Crystallin and alpha-B Crystallin sequence variations in cataract and in POAG patients. Invest Ophthalmol Vis Sci 2001;42 (ARVO Suppl):S291-1576.
  12. DSC Lam, Baum L, Leung YF, Tam POS, Fan DSP, Pang CP. Linkage analysis to locate a gene for myopia. 18th Congress of the Asia-Pacific Academy of Ophthalmology. Taiwan 10-14 March 2001. PI-08.
  13. Leung YF, Pang CP, Baum L, Chua JKH, Chan KP, Lam DSC. Is the TIGR-MYOC gene necessary for normal eye function? The Third International Symposium of Ophthalmology (ISO) and Symposium of the Asia-Pacific Society of Eye Genetics. Hong Kong. 2-4 February 2001. Scientific Poster 3.
  14. Baum L, Leung YF, Fan DSP, Tam POS, Pang CP, Lam DSC. Locate a Myopia gene by linkage analysis. The Third International Symposium of Ophthalmology (ISO) and Symposium of the Asia-Pacific Society of Eye Genetics. Hong Kong. 2-4 February 2001. Scientific Poster 5.
  15. Lee WS, Tong WC, Leung YF, Baum L, Fan DSP, Pang CP. Study on the TIGR/ MYOC Promoter Sequence. The Third International Symposium of Ophthalmology (ISO) and Symposium of the Asia-Pacific Society of Eye Genetics. Hong Kong. 2-4 February 2001. Scientific Poster 7.
  16. Leung YF, Pang CP, Baum L, Chua JKH, Tam POS, Choy KW, Lam DSC. Is TIGR-MYOC necessary for normal eye function?.  The 3rd HUGO Pacific Meeting and the 4th Asia-Pacific Conference on Human Genetics. Shanghai, China. 18-21 October 2000.
  17. Leung YF, Chua JKH, Baum L, Fan DSP, Lam DSC, Pang CP. Sequence variations in the TIGR gene. 18th International Congress of Biochemistry and Molecular Biology. Birmingham, UK 16-20 Jul 2000. Abstract 1041.
  18. Lam DSC, Lau TC, Leung YF, Wong PB, Baum L, Pang CP. Association between a TIGR polymorphism and high myopia. Invest Ophthalmol Vis Sci; 2000:41 (ARVO Suppl):S30-154.
  19. Wong HL, Leung YF, Tam POS, Baum L, Choy KW, Lam DSC, Pang CP. Methods to find both homozygous and heterozygous mutations using conformation sensitive gel electrophoresis. Invest Ophthalmol Vis Sci 2000;41 (ARVO Suppl):S29-147.
  20. Tong WC, Leung YF, Baum L, Fan DSP, Lam DSC, Pang CP. TIGR promoter sequence variations in primary open angle glaucoma. Invest Ophthalmol Vis Sci 2000;41 (ARVO Suppl):S821-4357.
  21. Baum L, Leung YF, Tam POS, Choy KW, Lam DSC, Pang CP. Detection of homozygous sequence alterations by conforation sensitive gel electrophoresis. 2nd IFCC-Roche Conference on Human Genomics. Kyoto, Japan. 16-19 April 2000. Abstracts 78.
  22. Leung YF, Tam POS, Baum L, Lam DSC, Chan WM, Pang CP. Cost savings using automated DNA sequencing. 2nd IFCC-Roche Conference on Human Genomics. Kyoto, Japan. 16-19 April 2000. Abstracts 92.
  23. Pang CP, Chua JKH, Leung YF, Lam DSC. Investigation for TIGR mutations in the Chinese population. Asian-Oceanic Glaucoma Society. Tokyo, Japan. 1999;127.
  24. Leung YF, Fan DSP, Chan WM, Baum L, Pang CP, Lam DSC. Apolipoprotein E alleles in age-related macular degeneration. Invest Ophthalmol Vis Sci 1999;40 (ARVO Suppl):S920-4849.
  25. Pang CP, Chua JKH, Leung YF, Choy KW, Fan DSP, Lam DSC. Sequence alterations in the TIGR gene in Chinese patients with primary open angle glaucoma. Invest Ophthalmol Vis Sci 1999;40 (ARVO Suppl):S510-2692.
Last updated: 17 Sep 2004
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