My favorite proteomics books

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Structural Bioinformatics
by Philip E. Bourne (Editor), Helge Weissig (Editor)
Paperback: 672 pages ; Dimensions (in inches): 1.30 x 10.08 x 7.04; Publisher: John Wiley & Sons; (February 2003); ISBN: 0471201995

Price: $69.95
Table of contents

Editorial Reviews From Book News, Inc.
Bioinformatics develops methods for manipulating biological data to solve problems in biology. After reviewing the structure of protein, DNA, and RNA, this introduction to the field describes the methods used to derive macromolecular structure data, and the data formats and databases that represent and store the data. The 29 contributions characterize structure classification schemes, structure validation, secondary structure assignment, and protein interactions. Other topics include ligand design, homology modeling, and fold recognition methods. The book may be useful to working bioinformaticians, but is primarily intended for students.Book News, Inc.®, Portland, OR

Proteins and Proteomics: A Laboratory Manual
by Richard J. Simpson (Editor);
Paperback: 900 pages; Publisher: Cold Spring Harbor Laboratory; (December 1, 2002); ISBN: 0879695544

Price: $175.00

Editorial Reviews From Book News, Inc.
Written for both graduate students and experienced investigators, this manual describes the general principles, analytical methods, and protocols involved in the study of proteomics. Simpson (Joint Proteomics Laboratory, Australia) begins with polyacrylamide gel electrophoresis for the separation of proteins in complex mixtures and the preparation of cellular extracts. Further protocols are provided for reversed-phase liquid chromatography, amino- and carboxyl-terminal sequence analysis, and peptide mapping. The largest chapter consists of 13 protocols for using mass spectrometry to identify proteins. Each protocol lists the reagents and equipment required and step-by-step instructions for performing the method.Book News, Inc.®, Portland, OR

Proteomics in Practice
by Reiner Westermeier, Tom Naven
Hardcover: (July 2002);  Publisher: John Wiley & Sons; ISBN: 3527303545

Price: US$84.95

Editorial Reviews From Book News, Inc.
A guide to the analysis of proteins by 2D electrophoresis and mass spectroscopy, specifically the methods used for expression proteomics. The authors first review sample preparation, isoelectric focusing, sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS- PAGE), spot detection techniques, computer image analysis, and protein identification by database searching. The second half of the book provides detailed instructions for performing each step in the laboratory. Troubleshooting tables complete the manual.Book News, Inc.®, Portland, OR .

Proteomics : From Protein Sequence to Function 
by S. Pennington (Editor), M. Dunn (Editor)
Paperback - 304 pages (December 2000) Springer Verlag; ISBN: 0387915893

Price: US$44.95
Amazon.com customer ration: 

Reviewer: A reader from USA 
This book represents a collection of articles that review approaches and technologies useful in the analysis of global protein expression, or proteomics. An introduction to the relationship between genomics and so-called proteomics is followed by chapters devoted to genetic based methods to study protein expression, reviews of two-dimensional gel electrophroresis, mass spectrometry, image analysis, high throughput / automation and some applications. Despite the title of the book, there is little on protein function, and a major facet of proteomics, that is, quantitation is all but forgotten. Some chapters overly cite the authors own work and ignore others, some errors are also encountered. In Chapter 5 Patterson and co describe post souce decay or PSD as occuring IN the ion source and repeatedly refers to MS measurement of mass not, more correctly, mass-to-charge. 

Proteome Research : Two-Dimensional Gel Electrophoresis and Identification Methods (Principles and Practice)
by th Rabilloud (Editor), Thierry Rabilloud
Paperback - 270 pages (February 2000) Springer Verlag; ISBN: 3540657924 ; Dimensions (in inches): 0.65 x 9.27 x 6.12 

Price: US$49.60
Table of contents
Amazon.com customer rating:

Editorial Reviews Book Description
Two-dimensional electrophoresis is the central methodology in proteome research, and the state of the art is described in detail in this text, together with extensive coverage of the detection methods available. Sufficient detail is given to allow the readers to apply these technologies to their own particular requirements. 

Proteome and Protein Analysis
by R. M. Kamp (Editor), D. Kyriakidis (Editor), th Choli-Papadopoulou (Editor)
Hardcover (December 1999)  Springer Verlag; ISBN: 3540658912 

Price: US$125.00
Table of contents

Editorial Reviews Book Description 
Selected papers presented at the MPSA 98 are covering new, sensitive and rapid methods for the analysis of proteins, with special emphasis on the total cell proteins, the proteome. In addition to the experimental details, the advantages and limitations of the methodological approaches are discussed. Topics included are: Protein sequencing analysis, protein and peptide sample preparation, mass spectrometry, NMR, analysis of post-translational modifications, purification of recombinant proteins, protein-protein and protein-DNA interactions, structure prediction, modeling and protein folding, functional implications of protein domains and newly emerging methods for the investigation of the proteome, allowing to analyse the expression of genes 

2-D Proteome Analysis Protocols
by Andrew J. Link (Editor)
Hardcover - 601 pages 1st edition (January 15, 1999) Humana Pr; ISBN: 0896035247 ; Dimensions (in inches): 1.29 x 9.29 x 6.30 

Price: US$99.50
Table of contents

Editorial Reviews From Book News, Inc. 
Comprises 55 contributions that are intended as a guide both for novices to 2-D gels and for experienced practitioners who want to try the newer techniques. The contributions guide researchers through the complete process of working with 2-D protein gels from making the protein extract to finally identifying the proteins of interest. The volume includes protocols for generating 2-D protein extracts from most of  the standard model organisms, including bacteria, yeasts, nematodes, plants, mice, and humans. Each chapter includes a description of the protocol, the basic theory behind it, a list of the equipment and reagents necessary for the protocol, a step-by-step guide to the experiment, and hints for dealing with problems. Book News, Inc.®, Portland, OR 

Proteome Research : New Frontiers in Functional Genomics (Principles and Practice) 
by M. R. Wilkins (Editor), K. L. Williams (Editor), R. D. Appel (Editor),D.F. Hochstrasser
Paperback - 300 pages (December 1997) Springer Verlag; ISBN: 3540627537 ; Dimensions (in inches): 0.63 x 9.28 x 6.11 

Price: US$ 52.95
Table of contents
My rating: 

My comments:
This is a classic book on functional genomics. It covers the proteomics approach for functional genomics study like 2-D gel electrophoresis, the basics of Mass Spectroscopy applications on functional genomics, the databases, protein modelling and applications. 

Mass Spectrometry for Biotechnology 
by Gary Siuzdak 
Paperback - 161 pages (March 1996) Academic Pr; ISBN: 0126474710 ; Dimensions (in inches): 0.48 x 8.93 x 5.89 

Price: US$42.00
My rating:

It is an excellent book for an outsider to grasp the basic ideas about the two most promising technologies for proteomics: matrix-sssisted laser desorption/ionization time of flight (MALDI-TOF) and eletrospray ionization (ESI). Also covered are many other ionization techniques, the basics of detection and the analysis of raw data. Another excellent point is it is very thin ~ 140 pages, you can easily finish it within a day or two. A must buy for beginners.



last updated: 16 Jul 2003
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