My functional genomics journal watch - year 2004 Jul-Dec [ this week | 2004 Jul-Dec | 2004 Jan-Jun | 2003 Jul-Dec | 2003 Jan-Jun | 2002 | 2001 | 2000 | 1999 | 1998 ]

General
Genome
   Homo Sapiens/Human
   Mycoplasma mobile
   Propionibacterium acnes
Comparative Genomics
Population Genomics/Evolutionary Genomics
Network/pathway reconstruction and analysis
Metabolomics
Pharmacogenomics
Toxicogenomics
System Biology
Database
Applications
Single Nucleotide Polymorphisms (SNPs) & haplotyping (typing, validation and mapping)
Techniques & Tools
Ethical, Legal and Social issues		 Can't find the functional genomics article published in 2003 in my site? 
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General

  1. Hill DE, Brasch MA, Del Campo AA, Doucette-Stamm L, Garrels JI, Glaven J, Hartley JL, Hudson JR Jr, Moore T, Vidal M. Academia-industry collaboration: an integral element for building "omic" resources. Genome Res. 2004 Oct;14(10B):2010-4. [PubMed]
  2. Brent R. A partnership between biology and engineering. Nat Biotechnol. 2004 Oct;22(10):1211-4. [PubMed]
  3. Hughes TR, Robinson MD, Mitsakakis N, Johnston M. The promise of functional genomics: completing the encyclopedia of a cell. Curr Opin Microbiol. 2004 Oct;7(5):546-54. [PubMed]
  4. Stamatoyannopoulos JA. The genomics of gene expression. Genomics. 2004 Sep;84(3):449-57. [PubMed]
  5. Tautz D, Lassig M. Of statistics and genomes. Trends Genet. 2004 Aug;20(8):344-6. [PubMed]

Genome

  1. Crossman L, Holden M, Pain A, Parkhill J. Genomes beyond compare. Nat Rev Microbiol. 2004 Aug;2(8):616-7.  [PubMed]
  2. Meyers BC, Scalabrin S, Morgante M. Mapping and sequencing complex genomes: let's get physical! Nat Rev Genet. 2004 Aug;5(8):578-88. [PubMed]

Homo Sapiens/Human

  1. Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM. The DNA sequence and comparative analysis of human chromosome 5. Nature. 2004 Sep 16;431(7006):268-74. [PubMed]

Mycoplasma mobile

  1. Jaffe JD, Stange-Thomann N, Smith C, DeCaprio D, Fisher S, Butler J, Calvo S, Elkins T, FitzGerald MG, Hafez N, Kodira CD, Major J, Wang S, Wilkinson J, Nicol R, Nusbaum C, Birren B, Berg HC, Church GM. The Complete Genome and Proteome of Mycoplasma mobile. Genome Res. 2004 Aug;14(8):1447-61. [PubMed]

Propionibacterium acnes

  1. Bruggemann H, Henne A, Hoster F, Liesegang H, Wiezer A, Strittmatter A, Hujer S, Durre P, Gottschalk G. The complete genome sequence of Propionibacterium acnes, a commensal of human skin. Science. 2004 Jul 30;305(5684):671-3. [PubMed]

Comparative Genomics

  1. Blakesley RW, Hansen NF, Mullikin JC, Thomas PJ, McDowell JC, Maskeri B, Young AC, Benjamin B, Brooks SY, Coleman BI, Gupta J, Ho SL, Karlins EM, Maduro QL, Stantripop S, Tsurgeon C, Vogt JL, Walker MA, Masiello CA, Guan X, Bouffard GG, Green ED. An intermediate grade of finished genomic sequence suitable for comparative analyses. Genome Res. 2004 Nov;14(11):2235-44. [PubMed]  
  2. Ong C, Ooi CH, Wang D, Chong H, Ng KC, Rodrigues F, Lee MA, Tan P. Patterns of large-scale genomic variation in virulent and avirulent Burkholderia species. Genome Res. 2004 Nov;14(11):2295-307. [PubMed] 
  3. Mulley J, Holland P. Comparative genomics: small genome, big insights. Nature. 2004 Oct 21;431(7011):916-7. [PubMed]
  4. Ahituv N, Rubin EM, Nobrega MA. Exploiting human-fish genome comparisons for deciphering gene regulation. Hum Mol Genet. 2004 Oct 1;13 Suppl 2:R261-6. [PubMed]
  5. Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. Genome Res. 2004 Sep;14(9):1711-8. [PubMed]
  6. Coulson RM, Hall N, Ouzounis CA. Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum. Genome Res. 2004 Aug;14(8):1548-54. [PubMed]
  7. Ogura A, Ikeo K, Gojobori T. Comparative analysis of gene expression for convergent evolution of camera eye between octopus and human. Genome Res. 2004 Aug;14(8):1555-61. [PubMed]
  8. Huynen MA, Snel B, Van Noort V. Comparative genomics for reliable protein-function prediction from genomic data. Trends Genet. 2004 Aug;20(8):340-4. [PubMed]
  9. Piskur J, Langkjaer RB. Yeast genome sequencing: the power of comparative genomics. Mol Microbiol. 2004 Jul;53(2):381-389. [PubMed]

Population Genomics/Evolutionary Genomics

  1. Vallender EJ, Lahn BT. Positive selection on the human genome. Hum Mol Genet. 2004 Oct 1;13 Suppl 2:R245-54. [PubMed]
  2. Foster MW, Sharp RR. Beyond race: towards a whole-genome perspective on human populations and genetic variation. Nat Rev Genet. 2004 Oct;5(10):790-6.  [PubMed]
  3. Snel B, van Noort V, Huynen MA. Gene co-regulation is highly conserved in the evolution of eukaryotes and prokaryotes. Nucleic Acids Res. 2004 Sep 07;32(16):4725-31. [PubMed]
  4. Serre D, Paabo S. Evidence for gradients of human genetic diversity within and among continents. Genome Res. 2004 Sep;14(9):1679-85. [PubMed]
  5. She X, Horvath JE, Jiang Z, Liu G, Furey TS, Christ L, Clark R, Graves T, Gulden CL, Alkan C, Bailey JA, Sahinalp C, Rocchi M, Haussler D, Wilson RK, Miller W, Schwartz S, Eichler EE. The structure and evolution of centromeric transition regions within the human genome. Nature. 2004 Aug 19;430(7002):857-64. [PubMed]
  6. Zhong S, Khodursky A, Dykhuizen DE, Dean AM.  Evolutionary genomics of ecological specialization. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11719-24. [PubMed]
  7. Emes RD, Riley MC, Laukaitis CM, Goodstadt L, Karn RC, Ponting CP. Comparative Evolutionary Genomics of Androgen-Binding Protein Genes. Genome Res. 2004 Aug;14(8):1516-29. [PubMed]
  8. Grover CE, Kim H, Wing RA, Paterson AH, Wendel JF. Incongruent patterns of local and global genome size evolution in cotton. Genome Res. 2004 Aug;14(8):1474-82. [PubMed]
  9. Goffeau A. Evolutionary genomics: seeing double. Nature. 2004 Jul 1;430(6995):25-6. [PubMed]
  10. Dujon B, Sherman D, Fischer G, Durrens P, Casaregola S, Lafontaine I, De Montigny J, Marck C, Neuveglise C, Talla E, Goffard N, Frangeul L, Aigle M, Anthouard V, Babour A, Barbe V, Barnay S, Blanchin S, Beckerich JM, Beyne E, Bleykasten C, Boisrame A, Boyer J, Cattolico L, Confanioleri F, De Daruvar A, Despons L, Fabre E, Fairhead C, Ferry-Dumazet H, Groppi A, Hantraye F, Hennequin C, Jauniaux N, Joyet P, Kachouri R, Kerrest A, Koszul R, Lemaire M, Lesur I, Ma L, Muller H, Nicaud JM, Nikolski M, Oztas S, Ozier-Kalogeropoulos O, Pellenz S, Potier S, Richard GF, Straub ML, Suleau A, Swennen D, Tekaia F, Wesolowski-Louvel M, Westhof E, Wirth B, Zeniou-Meyer M, Zivanovic I, Bolotin-Fukuhara M, Thierry A, Bouchier C, Caudron B, Scarpelli C, Gaillardin C, Weissenbach J, Wincker P, Souciet JL. Genome evolution in yeasts. Nature. 2004 Jul 1;430(6995):35-44. [PubMed]

Network/pathway reconstruction and analysis

  1. Harbison CT, Gordon DB, Lee TI, Rinaldi NJ, Macisaac KD, Danford TW, Hannett NM, Tagne JB, Reynolds DB, Yoo J, Jennings EG, Zeitlinger J, Pokholok DK, Kellis M, Rolfe PA, Takusagawa KT, Lander ES, Gifford DK, Fraenkel E, Young RA. Transcriptional regulatory code of a eukaryotic genome. Nature. 2004 Sep 2;431(7004):99-104. [PubMed]
  2. Hartman JL 4th, Tippery NP. Systematic quantification of gene interactions by phenotypic array analysis. Genome Biol. 2004;5(7):R49. [PubMed]

Metabolomics

  1. Jansen JJ, Hoefsloot HC, Boelens HF, van der Greef J, Smilde AK. Analysis of longitudinal metabolomics data. Bioinformatics. 2004 Oct 12;20(15):2438-46. [PubMed]
  2. Fernie AR, Trethewey RN, Krotzky AJ, Willmitzer L. Innovation: Metabolite profiling: from diagnostics to systems biology. Nat Rev Mol Cell Biol. 2004 Sep;5(9):763-9. [PubMed]
  3. Villas-Boas SG, Mas S, Akesson M, Smedsgaard J, Nielsen J. Mass spectrometry in metabolome analysis. Mass Spectrom Rev. 2004 Aug 19 [Epub ahead of print] [PubMed]
  4. Hirai MY, Yano M, Goodenowe DB, Kanaya S, Kimura T, Awazuhara M, Arita M, Fujiwara T, Saito K. From The Cover: Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10205-10. [PubMed]
  5. Oksman-Caldentey KM, Inze D, Oresic M. Connecting genes to metabolites by a systems biology approach. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):9949-50. [PubMed]

Pharmacogenomics

  1. Kramer R, Cohen D. Functional genomics to new drug targets. Nat Rev Drug Discov. 2004 Nov;3(11):965-72. [PubMed] 
  2. Nebert DW, Vesell ES. Advances in pharmacogenomics and individualized drug therapy: exciting challenges that lie ahead. Eur J Pharmacol. 2004 Oct 1;500(1-3):267-280. [PubMed]
  3. Hood L, Perlmutter RM. The impact of systems approaches on biological problems in drug discovery. Nat Biotechnol. 2004 Oct;22(10):1215-7. [PubMed]
  4. Butcher EC, Berg EL, Kunkel EJ. Systems biology in drug discovery. Nat Biotechnol. 2004 Oct;22(10):1253-9. [PubMed]
  5. Lesko LJ, Woodcock J. Opinion: Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective. Nat Rev Drug Discov. 2004 Sep;3(9):763-9. [PubMed]
  6. Meyer UA. Timeline: Pharmacogenetics - five decades of therapeutic lessons from genetic diversity. Nat Rev Genet. 2004 Sep;5(9):669-76. [PubMed]
  7. Roses AD. Pharmacogenetics and drug development: the path to safer and more effective drugs. Nat Rev Genet. 2004 Sep;5(9):645-56. [PubMed]
  8. Weinshilboum R, Wang L. Pharmacogenomics: bench to bedside. Nat Rev Drug Discov. 2004 Sep;3(9):739-48. [PubMed]
  9. Chang JT, Altman RB. Extracting and characterizing gene-drug relationships from the literature. Pharmacogenetics. 2004 Sep;14(9):577-86. [PubMed]

Toxicogenomics

  1. Watters JW, Kraja A, Meucci MA, Province MA, McLeod HL. Genome-wide discovery of loci influencing chemotherapy cytotoxicity. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11809-14. [PubMed]

System Biology

  1. Kitano H. Biological robustness. Nat Rev Genet. 2004 Nov;5(11):826-37. [PubMed] 
  2. Hood L, Perlmutter RM. The impact of systems approaches on biological problems in drug discovery. Nat Biotechnol. 2004 Oct;22(10):1215-7. [PubMed]
  3. Westerhoff HV, Palsson BO. The evolution of molecular biology into systems biology. Nat Biotechnol. 2004 Oct;22(10):1249-52. [PubMed]
  4. Stephanopoulos G, Alper H, Moxley J. Exploiting biological complexity for strain improvement through systems biology. Nat Biotechnol. 2004 Oct;22(10):1261-7. [PubMed]
  5. Nicholson JK, Holmes E, Lindon JC, Wilson ID. The challenges of modeling mammalian biocomplexity. Nat Biotechnol. 2004 Oct;22(10):1268-74. [PubMed]
  6. Butcher EC, Berg EL, Kunkel EJ. Systems biology in drug discovery. Nat Biotechnol. 2004 Oct;22(10):1253-9. [PubMed]
  7. Glaser P, Boone C. Genomics Beyond the genome: from genomics to systems biology. Curr Opin Microbiol. 2004 Oct;7(5):489-91. [PubMed]
  8. Hood L, Heath JR, Phelps ME, Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science. 2004 Oct 22;306(5696):640-3. [PubMed] 
  9. Oksman-Caldentey KM, Inze D, Oresic M. Connecting genes to metabolites by a systems biology approach. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):9949-50. [PubMed]

Database

Applications

  1. Jeong KS, Ahn J, Khodursky AB. Spatial patterns of transcriptional activity in the chromosome of Escherichia coli. Genome Biol. 2004;5(11):R86. [PubMed] 
  2. Schwartz DA, Freedman JH, Linney EA. Environmental genomics: a key to understanding biology, pathophysiology and disease. Hum Mol Genet. 2004 Oct 1;13 Suppl 2:R217-24.  [PubMed]
  3. Palsson B. Two-dimensional annotation of genomes. Nat Biotechnol. 2004 Oct;22(10):1218-9. [PubMed]
  4. Friedman A, Perrimon N. Genome-wide high-throughput screens in functional genomics. Curr Opin Genet Dev. 2004 Oct;14(5):470-6. [PubMed]
  5. Stathopoulos A, Levine M. Whole-genome analysis of Drosophila gastrulation. Curr Opin Genet Dev. 2004 Oct;14(5):477-84. [PubMed]
  6. Furey TS, Diekhans M, Lu Y, Graves TA, Oddy L, Randall-Maher J, Hillier LW, Wilson RK, Haussler D. Analysis of Human mRNAs With the Reference Genome Sequence Reveals Potential Errors, Polymorphisms, and RNA Editing. Genome Res. 2004 Oct;14(10B):2034-40.[PubMed]
  7. Dupuy D, Li QR, Deplancke B, Boxem M, Hao T, Lamesch P, Sequerra R, Bosak S, Doucette-Stamm L, Hope IA, Hill DE, Walhout AJ, Vidal M. A First Version of the Caenorhabditis elegans Promoterome. Genome Res. 2004 Oct;14(10B):2169-75. [PubMed]
  8. Genetics 2004 Oct, issue on wheat investigation
  9. Wang XJ, Reyes JL, Chua NH, Gaasterland T. Prediction and identification of Arabidopsis thaliana microRNAs and their mRNA targets. Genome Biol. 2004;5(9):R65. [PubMed]
  10. Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, De Angelis MH, Jackson I, Kioussis D, Kollias G, Lathrop M, Lendahl U, Malumbres M, Von Melchner H, Muller W, Partanen J, Ricciardi-Castagnoli P, Rigby P, Rosen B, Rosenthal N, Skarnes B, Stewart AF, Thornton J, Tocchini-Valentini G, Wagner E, Wahli W, Wurst W. The European dimension for the mouse genome mutagenesis program. Nat Genet. 2004 Sep;36(9):925-7. [PubMed]
  11. Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B. The knockout mouse project. Nat Genet. 2004 Sep;36(9):921-4. [PubMed]
  12. Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C. Detection of large-scale variation in the human genome. Nat Genet. 2004 Sep;36(9):949-51. [PubMed]
  13. Sato TK, Panda S, Miraglia LJ, Reyes TM, Rudic RD, McNamara P, Naik KA, FitzGerald GA, Kay SA, Hogenesch JB. A functional genomics strategy reveals rora as a component of the Mammalian circadian clock. Neuron. 2004 Aug 19;43(4):527-37. [PubMed]
  14. Kosman D, Mizutani CM, Lemons D, Cox WG, McGinnis W, Bier E. Multiplex detection of RNA expression in Drosophila embryos. Science. 2004 Aug 6;305(5685):846. [PubMed]
  15. Meyers BC, Vu TH, Tej SS, Ghazal H, Matvienko M, Agrawal V, Ning J, Haudenschild CD. Analysis of the transcriptional complexity of Arabidopsis thaliana by massively parallel signature sequencing. Nat Biotechnol. 2004 Aug;22(8):1006-11. [PubMed]
  16. Roh TY, Ngau WC, Cui K, Landsman D, Zhao K. High-resolution genome-wide mapping of histone modifications. Nat Biotechnol. 2004 Aug;22(8):1013-6. [PubMed]
  17. Fraser AG, Marcotte EM. Development through the eyes of functional genomics. Curr Opin Genet Dev. 2004 Aug;14(4):336-42. [PubMed]
  18. Kas MJ, Van Ree JM. Dissecting complex behaviours in the post-genomic era. Trends Neurosci. 2004 Jul;27(7):366-9. [PubMed]
  19. Brunner HG, van Driel MA. From syndrome families to functional genomics. Nat Rev Genet. 2004 Jul;5(7):545-51. [PubMed]

Single Nucleotide Polymorphisms (SNPs) & haplotyping (typing, validation and mapping)

  1. Becker T, Knapp M. A Powerful Strategy to Account for Multiple Testing in the Context of Haplotype Analysis. Am J Hum Genet. 2004 Oct;75(4):561-70.[PubMed]
  2. Halldorsson BV, Bafna V, Lippert R, Schwartz R, De La Vega FM, Clark AG, Istrail S. Optimal Haplotype Block-Free Selection of Tagging SNPs for Genome-Wide Association Studies. Genome Res. 2004 Aug;14(8):1633-40. [PubMed]
  3. Nelson MR, Marnellos G, Kammerer S, Hoyal CR, Shi MM, Cantor CR, Braun A. Large-scale validation of single nucleotide polymorphisms in gene regions. Genome Res. 2004 Aug;14(8):1664-8. [PubMed]
  4. Zhang K, Sun F, Zhao H. HAPLORE: a program for haplotype reconstruction in general pedigrees without recombination. Bioinformatics. 2004 Jul 1;. [Epub ahead of print][PubMed]
  5. Fakhrai-Rad H, Zheng J, Willis TD, Wong K, Suyenaga K, Moorhead M, Eberle J, Thorstenson YR, Jones T, Davis RW, Namsaraev E, Faham M. SNP discovery in pooled samples with mismatch repair detection. Genome Res. 2004 Jul;14(7):1404-12. [PubMed]
  6. Greenwood TA, Rana BK, Schork NJ. Human haplotype block sizes are negatively correlated with recombination rates. Genome Res. 2004 Jul;14(7):1358-61. [PubMed]

Techniques & Tools

  1. Pan X, Yuan DS, Xiang D, Wang X, Sookhai-Mahadeo S, Bader JS, Hieter P, Spencer F, Boeke JD. A robust toolkit for functional profiling of the yeast genome. Mol Cell. 2004 Nov 5;16(3):487-96. [PubMed]  
  2. Liew CC, Dzau VJ. Molecular genetics and genomics of heart failure. Nat Rev Genet. 2004 Nov;5(11):811-25. [PubMed]
  3. Weaver T, Maurer J, Hayashizaki Y. Sharing genomes: an integrated approach to funding, managing and distributing genomic clone resources. Nat Rev Genet. 2004 Nov;5(11):861-6. [PubMed] 
  4. Brasch MA, Hartley JL, Vidal M. ORFeome Cloning and Systems Biology: Standardized Mass Production of the Parts From the Parts-List. Genome Res. 2004 Oct;14(10B):2001-9. [PubMed]
  5. Rual JF, Hirozane-Kishikawa T, Hao T, Bertin N, Li S, Dricot A, Li N, Rosenberg J, Lamesch P, Vidalain PO, Clingingsmith TR, Hartley JL, Esposito D, Cheo D, Moore T, Simmons B, Sequerra R, Bosak S, Doucette-Stamm L, Le Peuch C, Vandenhaute J, Cusick ME, Albala JS, Hill DE, Vidal M. Human ORFeome Version 1.1: A Platform for Reverse Proteomics. Genome Res. 2004 Oct;14(10B):2128-35. [PubMed]
  6. Marsischky G, Labaer J. Many paths to many clones: a comparative look at high-throughput cloning methods. Genome Res. 2004 Oct;14(10B):2020-8. [PubMed]
  7. The MGC Project Team. The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10b):2121-2127. [PubMed]
  8. Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sultmann H, Poustka A. From ORFeome to Biology: A Functional Genomics Pipeline. Genome Res. 2004 Oct;14(10B):2136-44. [PubMed]
  9. Lamesch P, Milstein S, Hao T, Rosenberg J, Li N, Sequerra R, Bosak S, Doucette-Stamm L, Vandenhaute J, Hill DE, Vidal M. C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions. Genome Res. 2004 Oct;14(10B):2064-9.[PubMed]
  10. Sterky F, Bhalerao RR, Unneberg P, Segerman B, Nilsson P, Brunner AM, Charbonnel-Campaa L, Lindvall JJ, Tandre K, Strauss SH, Sundberg B, Gustafsson P, Uhlen M, Bhalerao RP, Nilsson O, Sandberg G, Karlsson J, Lundeberg J, Jansson S.  A Populus EST resource for plant functional genomics. Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13951-6. [PubMed]
  11. Petkov PM, Ding Y, Cassell MA, Zhang W, Wagner G, Sargent EE, Asquith S, Crew V, Johnson KA, Robinson P, Scott VE, Wiles MV. An efficient SNP system for mouse genome scanning and elucidating strain relationships. Genome Res. 2004 Sep;14(9):1806-11. [PubMed]
  12. Koch WH. Technology platforms for pharmacogenomic diagnostic assays. Nat Rev Drug Discov. 2004 Sep;3(9):749-61. [PubMed]
  13. Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Kel AE, Arakawa T, Carninci P, Kawai J, Hayashizaki Y, Takagi T, Nakai K, Sugano S. Large-scale collection and characterization of promoters of human and mouse genes. In Silico Biol. 2004 Jul 23;4(3):0036. [Epub ahead of print][PubMed]

Ethical, Legal and Social issues

  1. McCarthy J. Science and society: Tackling the challenges of interdisciplinary bioscience. Nat Rev Mol Cell Biol. 2004 Nov;5(11):933-7. [PubMed] 
  2. Cambon-Thomsen A. The social and ethical issues of post-genomic human biobanks. Nat Rev Genet. 2004 Nov;5(11):866-73. [PubMed] 
  3. Breckenridge A, Lindpaintner K, Lipton P, McLeod H, Rothstein M, Wallace H. Viewpoint: Pharmacogenetics: ethical problems and solutions. Nat Rev Genet. 2004 Sep;5(9):676-80. [PubMed]
  4. Howard K. Lack of data privacy could hamper pharmacogenomics studies. Nat Rev Drug Discov. 2004 Sep;3(9):725. [PubMed]
  5. Webster A, Martin P, Lewis G, Smart A. Science and society: Integrating pharmacogenetics into society: in search of a model. Nat Rev Genet. 2004 Sep;5(9):663-9.  [PubMed]
  6. Turner L. Bioethic$ Inc. Nat Biotechnol. 2004 Aug;22(8):947-948. [PubMed]
  7. Schubert L. Ethical implications of pharmacogenetics--do slippery slope arguments matter? Bioethics. 2004 Aug;18(4):361-78. [PubMed]
  8. Smart A, Martin P, Parker M. Tailored medicine: whom will it fit? The ethics of patient and disease stratification. Bioethics. 2004 Aug;18(4):322-42. [PubMed]
  9. van Delden J, Bolt I, Kalis A, Derijks J, Leufkens H. Tailor-made pharmacotherapy: future developments and ethical challenges in the field of pharmacogenomics. Bioethics. 2004 Aug;18(4):303-21. [PubMed]
  10. Lin Z, Owen AB, Altman RB. Genetics. Genomic research and human subject privacy. Science. 2004 Jul 9;305(5681):183. [PubMed]
last updated:  8 Dec 2004
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