My functional genomics journal watch - year 2003 Jan-Jun [ this week | 2004 Jul-Dec | 2004 Jan-Jun | 2003 Jul-Dec | 2003 Jan-Jun | 2002 | 2001 | 2000 | 1999 | 1998 ]

General
Genome 
   Bacillus cereus
   Bacteroides thetaiotaomicron
   Clostridium tetani
   Coronavirus
   Helicobacter hepaticus
   Helicobacter pylori
   Homo Sapiens/ Human
   Lactobacillus plantarum
   Leptospira interrogans
   Methanogenium frigidum and Methanococcoides burtonii
   Mus Musculus/ Mouse
   Neurospora crassa
   Rice
   Schizosaccharomyces pombe/ fission yeast
   Shigella flexneri
   Streptococcus pyogenes
   Streptomyces avermitilis
   Vibrio parahaemolyticus
Comparative Genomics
Population Genomics/Evolutionary Genomics
Behavioral Genomics (Behaviomics? :))
Network/pathway reconstruction and analysis
Metabolomics
Pharmacogenomics
Toxicogenomics
System Biology
Database
Applications
Single Nucleotide Polymorphisms (SNPs) & haplotyping (typing, validation and mapping)
Techniques & Tools
Ethical, Legal and Social issues		 Can't find the functional genomics article published in 2003 in my site? 
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General

  1. O'Brien TP, Bult CJ, Cremer C, Grunze M, Knowles BB, Langowski J, McNally J, Pederson T, Politz JC, Pombo A, Schmahl G, Spatz JP, Van Driel R. Genome function and nuclear architecture: from gene expression to nanoscience. Genome Res. 2003 Jun;13(6):1029-41. [PubMed][pdf]
  2. HUGO-a UN for the human genome. Nat Genet. 2003 Jun;34(2):115-116. [PubMed]
  3. Freimer N, Sabatti C. The Human Phenome Project. Nat Genet. 2003 May;34(1):15-21. [PubMed]
  4. Kellogg EA. What happens to genes in duplicated genomes. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4369-71. [PubMed][pdf]
  5. Collins FS, Morgan M, Patrinos A. The human genome project: lessons from large-scale biology. Science. 2003 Apr 11;300(5617):286-90. [PubMed]
  6. Frazier ME, Johnson GM, Thomassen DG, Oliver CE, Patrinos A. Realizing the potential of the genome revolution: the genomes to life program. Science. 2003 Apr 11;300(5617):290-3. [PubMed][web supplement]
  7. Jimenez-Sanchez G. Developing a Platform for Genomic Medicine in Mexico. Science. 2003 Apr 11;300(5617):295-296. [PubMed]
  8. Couzin J. Functional genomics. How to make sense of sequence. Science. 2003 Mar 14;299(5613):1642. [PubMed]
  9. Venter JC, Levy S, Stockwell T, Remington K, Halpern A. Massive parallelism, randomness and genomic advances. Nat Genet. 2003 Mar;33 Suppl:219-27. [PubMed]
  10. Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 2003 Mar;33 Suppl:245-54. [PubMed]
  11. Martin AC, Drubin DG. Impact of genome-wide functional analyses on cell biology research. Curr Opin Cell Biol. 2003 Feb;15(1):6-13. [PubMed]
  12. Yeatman TJ. The future of cancer management: translating the genome, transcriptome, and proteome. Ann Surg Oncol. 2003 Jan-Feb;10(1):7-14. [PubMed]
  13. Malaria after the genome. Nature. 2003 Jan 9;421(6919):97. [PubMed]

Genome

  1. Burt D, Pourquie O. Genetics. Chicken genome--science nuggets to come soon. Science. 2003 Jun 13;300(5626):1669. [PubMed][web supplement]
  2. Janssen P. Beyond 100 genomes. Genome Biol 2003 May; [PubMed]
  3. Iliopoulos I, Tsoka S, Andrade MA, Enright AJ, Carroll M, Poullet P, Promponas V, Liakopoulos T, Palaios G, Pasquier C, Hamodrakas S, Tamames J, Yagnik AT, Tramontano A, Devos D, Blaschke C, Valencia A, Brett D, Martin D, Leroy C, Rigoutsos I, Sander C, Ouzounis CA. Evaluation of annotation strategies using an entire genome sequence. Bioinformatics 2003 Apr 12; 19: 717-726. [PubMed]
  4. Evans JD, Gundersen-Rindal D. Beenomes to Bombyx: future directions in applied insect genomics. Genome Biol. 2003 Mar;4(3):107. [PubMed]
  5. Bamshad M, Wooding SP. Signatures of natural selection in the human genome. Nat Rev Genet. 2003 Feb;4(2):99-111.  [PubMed]
  6. Thomas JW, Touchman JW. Vertebrate genome sequencing: building a backbone for comparative genomics. Trends Genet. 2002 Feb;18(2):104-8. [PubMed]
  7. Olson MV, Varki A. Sequencing the chimpanzee genome: insights into human evolution and disease. Nat Rev Genet. 2003 Jan;4(1):20-8. [PubMed]

Bacillus cereus

  1. Parkhill J, Berry C. Genomics: Relative pathogenic values. Nature. 2003 May 1;423(6935):23-5. [PubMed]
  2. Ivanova N, Sorokin A, Anderson I, Galleron N, Candelon B, Kapatral V, Bhattacharyya A, Reznik G, Mikhailova N, Lapidus A, Chu L, Mazur M, Goltsman E, Larsen N, D'Souza M, Walunas T, Grechkin Y, Pusch G, Haselkorn R, Fonstein M, Dusko Ehrlich S, Overbeek R, Kyrpides N. Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis. Nature. 2003 May 1;423(6935):87-91. [PubMed][pdf][web supplement]
  3. Read TD, Peterson SN, Tourasse N, Baillie LW, Paulsen IT, Nelson KE, Tettelin H, Fouts DE, Eisen JA, Gill SR, Holtzapple EK, OKstad OA, Helgason E, Rilstone J, Wu M, Kolonay JF, Beanan MJ, Dodson RJ, Brinkac LM, Gwinn M, DeBoy RT, Madpu R, Daugherty SC, Durkin AS, Haft DH, Nelson WC, Peterson JD, Pop M, Khouri HM, Radune D, Benton JL, Mahamoud Y, Jiang L, Hance IR, Weidman JF, Berry KJ, Plaut RD, Wolf AM, Watkins KL, Nierman WC, Hazen A, Cline R, Redmond C, Thwaite JE, White O, Salzberg SL, Thomason B, Friedlander AM, Koehler TM, Hanna PC, Kolsto AB, Fraser CM. The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature. 2003 May 1;423(6935):81-6. [PubMed][pdf][web supplement]

Bacteroides thetaiotaomicron

  1. Xu J, Bjursell MK, Himrod J, Deng S, Carmichael LK, Chiang HC, Hooper LV, Gordon JI. A Genomic View of the Human-Bacteroides thetaiotaomicron Symbiosis. Science. 2003 Mar 28; 299: 2074-2076. [PubMed][web supplement]

Clostridium tetani

  1. Bruggemann H, Baumer S, Fricke WF, Wiezer A, Liesegang H, Decker I, Herzberg C, Martinez-Arias R, Merkl R, Henne A, Gottschalk G. The genome sequence of Clostridium tetani, the causative agent of tetanus disease. Proc Natl Acad Sci U S A 2003 Feb 4;100(3):1316-21 [PubMed]

Coronavirus

  1. Holmes KV, Enjuanes L. Virology. The SARS coronavirus: a postgenomic era. Science. 2003 May 30;300(5624):1377-8. [PubMed]
  2. Rota PA, Oberste MS, Monroe SS, Nix WA, Campagnoli R, Icenogle JP, Penaranda S, Bankamp B, Maher K, Chen MH, Tong S, Tamin A, Lowe L, Frace M, DeRisi JL, Chen Q, Wang D, Erdman DD, Peret TC, Burns C, Ksiazek TG, Rollin PE, Sanchez A, Liffick S, Holloway B, Limor J, McCaustland K, Olsen-Rasmussen M, Fouchier R, Gunther S, Osterhaus AD, Drosten C, Pallansch MA, Anderson LJ, Bellini WJ. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science. 2003 May 30;300(5624):1394-9. [PubMed][web supplement]
  3. Marra MA, Jones SJ, Astell CR, Holt RA, Brooks-Wilson A, Butterfield YS, Khattra J, Asano JK, Barber SA, Chan SY, Cloutier A, Coughlin SM, Freeman D, Girn N, Griffith OL, Leach SR, Mayo M, McDonald H, Montgomery SB, Pandoh PK, Petrescu AS, Robertson AG, Schein JE, Siddiqui A, Smailus DE, Stott JM, Yang GS, Plummer F, Andonov A, Artsob H, Bastien N, Bernard K, Booth TF, Bowness D, Czub M, Drebot M, Fernando L, Flick R, Garbutt M, Gray M, Grolla A, Jones S, Feldmann H, Meyers A, Kabani A, Li Y, Normand S, Stroher U, Tipples GA, Tyler S, Vogrig R, Ward D, Watson B, Brunham RC, Krajden M, Petric M, Skowronski DM, Upton C, Roper RL. The Genome sequence of the SARS-associated coronavirus. Science. 2003 May 30;300(5624):1399-404. [PubMed][web supplement]

Helicobacter hepaticus

  1. Suerbaum S, Josenhans C, Sterzenbach T, Drescher B, Brandt P, Bell M, Droge M, Fartmann B, Fischer HP, Ge Z, Horster A, Holland R, Klein K, Konig J, Macko L, Mendz GL, Nyakatura G, Schauer DB, Shen Z, Weber J, Frosch M, Fox JG. The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7901-6. [PubMed][pdf][web supplement]

Helicobacter pylori

  1. Boneca IG, Reuse Hd H, Epinat JC, Pupin M, Labigne A, Moszer I. A revised annotation and comparative analysis of Helicobacter pylori genomes. Nucleic Acids Res. 2003 Mar 15;31(6):1704-14. [PubMed]

Homo Sapiens/ Human

  1. Willard HF. Genome biology: Tales of the Y chromosome. Nature. 2003 Jun 19;423(6942):810-1, 813. [PubMed]
    Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, Cordum HS, Hillier L, Brown LG, Repping S, Pyntikova T, Ali J, Bieri T, Chinwalla A, Delehaunty A, Delehaunty K, Du H, Fewell G, Fulton L, Fulton R, Graves T, Hou SF, Latrielle P, Leonard S, Mardis E, Maupin R, McPherson J, Miner T, Nash W, Nguyen C, Ozersky P, Pepin K, Rock S, Rohlfing T, Scott K, Schultz B, Strong C, Tin-Wollam A, Yang SP, Waterston RH, Wilson RK, Rozen S, Page DC. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature. 2003 Jun 19;423(6942):825-37.  [PubMed]
  2. Innan H, Padhukasahasram B, Nordborg M. The pattern of polymorphism on human chromosome 21. Genome Res. 2003 Jun;13(6):1158-68. [PubMed][pdf]
  3. Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR, Kirkpatrick SJ, Rahman N, Friedman JM, Heng HH, Pelicci PG, Lo-Coco F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GA, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT, Herrick SR, Lemyre E, Farra CG, Kim HG, Summers AM, Gripp KW, Roberts W, Szatmari P, Winsor EJ, Grzeschik KH, Teebi A, Minassian BA, Kere J, Armengol L, Pujana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier DG, Mould SJ, Dohner H, Dohner K, Rommens JM, Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD, Tsui LC. Human Chromosome 7: DNA Sequence and Biology. Science 2003 May 2;300(5620):767-72 [PubMed][web supplement]
  4. Cheung J, Estivill X, Khaja R, MacDonald JR, Lau K, Tsui LC, Scherer SW. Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence. Genome Biol. 2003 Apr; 4: R25. [PubMed][pdf]
  5. Cozzarelli NR. Revisiting the independence of the publicly and privately funded drafts of the human genome. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3021. [PubMed][pdf]
  6. Waterston RH, Lander ES, Sulston JE. More on the sequencing of the human genome. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3022-3024. [PubMed][pdf]
  7. Adams MD, Sutton GG, Smith HO, Myers EW, Venter JC. The independence of our genome assemblies. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3025-3026. [PubMed][pdf]
  8. Kouprina N, Leem SH, Solomon G, Ly A, Koriabine M, Otstot J, Pak E, Dutra A, Zhao S, Barrett JC, Larionov V. Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast. EMBO Report 2003 Mar; 4: 257-262. [PubMed]
  9. Heilig R, Eckenberg R, Petit JL, Fonknechten N, Da Silva C, Cattolico L, Levy M, Barbe V, De Berardinis V, Ureta-Vidal A, Pelletier E, Vico V, Anthouard V, Rowen L, Madan A, Qin S, Sun H, Du H, Pepin K, Artiguenave F, Robert C, Cruaud C, Bruls T, Jaillon O, Friedlander L, Samson G, Brottier P, Cure S, Segurens B, Aniere F, Samain S, Crespeau H, Abbasi N, Aiach N, Boscus D, Dickhoff R, Dors M, Dubois I, Friedman C, Gouyvenoux M, James R, Madan A, Mairey-Estrada B, Mangenot S, Martins N, Menard M, Oztas S, Ratcliffe A, Shaffer T, Trask B, Vacherie B, Bellemere C, Belser C, Besnard-Gonnet M, Bartol-Mavel D, Boutard M, Briez-Silla S, Combette S, Dufosse-Laurent V, Ferron C, Lechaplais C, Louesse C, Muselet D, Magdelenat G, Pateau E, Petit E, Sirvain-Trukniewicz P, Trybou A, Vega-Czarny N, Bataille E, Bluet E, Bordelais I, Dubois M, Dumont C, Guerin T, Haffray S, Hammadi R, Muanga J, Pellouin V, Robert D, Wunderle E, Gauguet G, Roy A, Sainte-Marthe L, Verdier J, Verdier-Discala C, Hillier L, Fulton L, McPherson J, Matsuda F, Wilson R, Scarpelli C, Gyapay G, Wincker P, Saurin W, Quetier F, Waterston R, Hood L, Weissenbach J. The DNA sequence and analysis of human chromosome 14. Nature. 2003 Feb 6;421(6923):601-7. [PubMed][web supplement]

Lactobacillus plantarum

  1. Kleerebezem M, Boekhorst J, Van Kranenburg R, Molenaar D, Kuipers OP, Leer R, Tarchini R, Peters SA, Sandbrink HM, Fiers MW, Stiekema W, Lankhorst RM, Bron PA, Hoffer SM, Groot MN, Kerkhoven R, De Vries M, Ursing B, De Vos WM, Siezen RJ. Complete genome sequence of Lactobacillus plantarum WCFS1. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1990-1995. [PubMed][pdf]

Leptospira interrogans

  1. Ren SX, Fu G, Jiang XG, Zeng R, Miao YG, Xu H, Zhang YX, Xiong H, Lu G, Lu LF, Jiang HQ, Jia J, Tu YF, Jiang JX, Gu WY, Zhang YQ, Cai Z, Sheng HH, Yin HF, Zhang Y, Zhu GF, Wan M, Huang HL, Qian Z, Wang SY, Ma W, Yao ZJ, Shen Y, Qiang BQ, Xia QC, Guo XK, Danchin A, Saint Girons I, Somerville RL, Wen YM, Shi MH, Chen Z, Xu JG, Zhao GP. Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing. Nature. 2003 Apr 24;422(6934):888-893. [PubMed][pdf][web supplement]

Methanogenium frigidum and Methanococcoides burtonii

  1. Saunders NF, Thomas T, Curmi PM, Mattick JS, Kuczek E, Slade R, Davis J, Franzmann PD, Boone D, Rusterholtz K, Feldman R, Gates C, Bench S, Sowers K, Kadner K, Aerts A, Dehal P, Detter C, Glavina T, Lucas S, Richardson P, Larimer F, Hauser L, Land M, Cavicchioli R. Mechanisms of Thermal Adaptation Revealed From the Genomes of the Antarctic Archaea Methanogenium frigidum and Methanococcoides burtonii. Genome Res. 2003 Jun 12 [Epub ahead of print] [PubMed][pdf]

Mus Musculus/ Mouse

  1. Rossant J et al., The mouse genome sequence - the end of the tail, or just the beginning? Genome Biol. 2003 Apr; 4: 109. [PubMed]
  2. Xuan Z, Wang J, Zhang MQ. Computational comparison of two mouse draft genomes and the human golden path. Genome Biol. 2003 Jan;4(1):R1. [PubMed][pdf]

Neurospora crassa

  1. Arnold J, Hilton N. Genome sequencing: Revelations from a bread mould. Nature. 2003 Apr 24;422(6934):821-2. [PubMed]
  2. Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma LJ, Smirnov S, Purcell S, Rehman B, Elkins T, Engels R, Wang S, Nielsen CB, Butler J, Endrizzi M, Qui D, Ianakiev P, Bell-Pedersen D, Nelson MA, Werner-Washburne M, Selitrennikoff CP, Kinsey JA, Braun EL, Zelter A, Schulte U, Kothe GO, Jedd G, Mewes W, Staben C, Marcotte E, Greenberg D, Roy A, Foley K, Naylor J, Stange-Thomann N, Barrett R, Gnerre S, Kamal M, Kamvysselis M, Mauceli E, Bielke C, Rudd S, Frishman D, Krystofova S, Rasmussen C, Metzenberg RL, Perkins DD, Kroken S, Cogoni C, Macino G, Catcheside D, Li W, Pratt RJ, Osmani SA, DeSouza CP, Glass L, Orbach MJ, Berglund JA, Voelker R, Yarden O, Plamann M, Seiler S, Dunlap J, Radford A, Aramayo R, Natvig DO, Alex LA, Mannhaupt G, Ebbole DJ, Freitag M, Paulsen I, Sachs MS, Lander ES, Nusbaum C, Birren B. The genome sequence of the filamentous fungus Neurospora crassa. Nature. 2003 Apr 24;422(6934):859-68. [PubMed][pdf][web supplement]

Rice

  1. Cyranoski D. Rice genome: A recipe for revolution? Nature. 2003 Apr 24;422(6934):796-8. [PubMed]

Schizosaccharomyces pombe/ fission yeast

  1. Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Schafer M, Muller-Auer S, Gabel C, Fuchs M, Dusterhoft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dreano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, Sanchez M, Del Rey F, Benito J, Dominguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P. Corrigendum: The genome sequence of Schizosaccharomyces pombe. Nature. 2003 Jan 2;421(6918):94. [PubMed]

Shigella flexneri

  1. Wei J, Goldberg MB, Burland V, Venkatesan MM, Deng W, Fournier G, Mayhew GF, Plunkett III G, Rose DJ, Darling A, Mau B, Perna NT, Payne SM, Runyen-Janecky LJ, Zhou S, Schwartz DC, Blattner FR. Complete Genome Sequence and Comparative Genomics of Shigella flexneri Serotype 2a Strain 2457T. Infect Immun. 2003 May;71(5):2775-2786. [PubMed]

Streptococcus pyogenes

  1. Nakagawa I, Kurokawa K, Yamashita A, Nakata M, Tomiyasu Y, Okahashi N, Kawabata S, Yamazaki K, Shiba T, Yasunaga T, Hayashi H, Hattori M, Hamada S. Genome Sequence of an M3 Strain of Streptococcus pyogenes Reveals a Large-Scale Genomic Rearrangement in Invasive Strains and New Insights into Phage Evolution. Genome Res. 2003 Jun;13(6):1042-55. [PubMed][pdf][web supplement]

Streptomyces avermitilis

  1. Hopwood DA. The Streptomyces genome-be prepared! Nat Biotechnol. 2003 May;21(5):505-6. [PubMed]
  2. Ikeda H, Ishikawa J, Hanamoto A, Shinose M, Kikuchi H, Shiba T, Sakaki Y, Hattori M, Omura S. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat Biotechnol 2003 May;21(5):526-31 [PubMed][web supplement]

Vibrio parahaemolyticus

  1. Makino K, Oshima K, Kurokawa K, Yokoyama K, Uda T, Tagomori K, Iijima Y, Najima M, Nakano M, Yamashita A, Kubota Y, Kimura S, Yasunaga T, Honda T, Shinagawa H, Hattori M, Iida T. Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V cholerae. Lancet 2003 Mar 1; 361. [PubMed]

Comparative Genomics

  1. Jiang Y, Doolittle RF. The evolution of vertebrate blood coagulation as viewed from a comparison of puffer fish and sea squirt genomes. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7527-32. [PubMed][pdf][web supplement]
  2. Mineta K, Nakazawa M, Cebria F, Ikeo K, Agata K, Gojobori T. Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7666-71 [PubMed][pdf][web supplement]
  3. Wildman DE, Uddin M, Liu G, Grossman LI, Goodman M. Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: Enlarging genus Homo. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7181-8. [PubMed][pdf][web supplement]
  4. Oduru S, Campbell JL, Karri S, Hendry WJ 3rd, Khan SA, Williams SC. Gene discovery in the hamster: a comparative genomics approach for gene annotation by sequencing of hamster testis cDNAs.  BMC Genomics. 2003 Jun 3;4(1):22. [PubMed][pdf]
  5. Nurtdinov RN, Artamonova II, Mironov AA, Gelfand MS. Low conservation of alternative splicing patterns in the human and mouse genomes. Hum Mol Genet. 2003 Jun 1;12(11):1313-1320. [PubMed]
  6. Modrek B, Lee CJ. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat Genet. 2003 Jun;34(2):177-80. [PubMed]
  7. Williams SH, Mouchel N, Harris A.  A comparative genomic analysis of the cow, pig, and human CFTR genes identifies potential intronic regulatory elements. Genomics. 2003 Jun;81(6):628-39.  [PubMed]
  8. Panopoulou G, Hennig S, Groth D, Krause A, Poustka AJ, Herwig R, Vingron M, Lehrach H. New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes. Genome Res. 2003 Jun;13(6):1056-66. [PubMed][pdf][web supplement]
  9. Santini S, Boore JL, Meyer A. Evolutionary conservation of regulatory elements in vertebrate hox gene clusters. Genome Res. 2003 Jun;13(6):1111-22. [PubMed][pdf][web supplement]
  10. Karlin S, Mrazek J, Gentles AJ. Genome comparisons and analysis. Curr Opin Struct Biol. 2003 Jun;13(3):344-52.  [PubMed]
  11. Slezak T, Kuczmarski T, Ott L, Torres C, Medeiros D, Smith J, Truitt B, Mulakken N, Lam M, Vitalis E, Zemla A, Zhou CE, Gardner S. Comparative genomics tools applied to bioterrorism defence. Brief Bioinform. 2003 Jun;4(2):133-49. [PubMed]
  12. Chain P, Kurtz S, Ohlebusch E, Slezak T. An applications-focused review of comparative genomics tools: capabilities, limitations and future challenges. Brief Bioinform. 2003 Jun;4(2):105-23. [PubMed]
  13. Salzberg SL. Genomics: Yeast rises again. Nature. 2003 May 15;423(6937):233-4. [PubMed]
  14. Kellis M, Patterson N, Endrizzi M, Birren B, Lander ES. Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature. 2003 May 15;423(6937):241-54. [PubMed][web supplement]
  15. Weill M, Lutfalla G, Mogensen K, Chandre F, Berthomieu A, Berticat C, Pasteur N, Philips A, Fort P, Raymond M. Comparative genomics: Insecticide resistance in mosquito vectors. Nature. 2003 May 8;423(6936):136-7. [PubMed]
  16. Modrek B, Lee CJ. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat Genet. 2003 May 5 [epub ahead of print] [PubMed]
  17. Ivanova N, Sorokin A, Anderson I, Galleron N, Candelon B, Kapatral V, Bhattacharyya A, Reznik G, Mikhailova N, Lapidus A, Chu L, Mazur M, Goltsman E, Larsen N, D'Souza M, Walunas T, Grechkin Y, Pusch G, Haselkorn R, Fonstein M, Dusko Ehrlich S, Overbeek R, Kyrpides N. Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis. Nature. 2003 May 1;423(6935):87-91. [PubMed][pdf][web supplement]
  18. Read TD, Peterson SN, Tourasse N, Baillie LW, Paulsen IT, Nelson KE, Tettelin H, Fouts DE, Eisen JA, Gill SR, Holtzapple EK, OKstad OA, Helgason E, Rilstone J, Wu M, Kolonay JF, Beanan MJ, Dodson RJ, Brinkac LM, Gwinn M, DeBoy RT, Madpu R, Daugherty SC, Durkin AS, Haft DH, Nelson WC, Peterson JD, Pop M, Khouri HM, Radune D, Benton JL, Mahamoud Y, Jiang L, Hance IR, Weidman JF, Berry KJ, Plaut RD, Wolf AM, Watkins KL, Nierman WC, Hazen A, Cline R, Redmond C, Thwaite JE, White O, Salzberg SL, Thomason B, Friedlander AM, Koehler TM, Hanna PC, Kolsto AB, Fraser CM. The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature. 2003 May 1;423(6935):81-6. [PubMed][pdf][web supplement]
  19. Hellmann I, Zollner S, Enard W, Ebersberger I, Nickel B, Paabo S. Selection on human genes as revealed by comparisons to chimpanzee cDNA. Genome Res. 2003 May;13(5):831-7. [PubMed]
  20. Neafsey DE, Palumbi SR. Genome size evolution in pufferfish: a comparative analysis of diodontid and tetraodontid pufferfish genomes. Genome Res. 2003 May;13(5):821-30. [PubMed]
  21. Pozzoli U, Elgar G, Cagliani R, Riva L, Comi GP, Bresolin N, Bardoni A, Sironi M. Comparative analysis of vertebrate dystrophin Loci indicate intron gigantism as a common feature. Genome Res. 2003 May;13(5):764-72. [PubMed]
  22. Hazen SP, Hawley RM, Davis GL, Henrissat B, Walton JD. Quantitative trait Loci and comparative genomics of cereal cell wall composition. Plant Physiol. 2003 May;132(1):263-71. [PubMed]
  23. Carroll SB. Genetics and the making of Homo sapiens. Nature. 2003 Apr 24;422(6934):849-57. [PubMed]
  24. Pedulla ML, Ford ME, Houtz JM, Karthikeyan T, Wadsworth C, Lewis JA, Jacobs-Sera D, Falbo J, Gross J, Pannunzio NR, Brucker W, Kumar V, Kandasamy J, Keenan L, Bardarov S, Kriakov J, Lawrence JG, Jacobs WR, Hendrix RW, Hatfull GF. Origins of Highly Mosaic Mycobacteriophage Genomes. Cell. 2003 Apr 18; 113:171-182. [PubMed]
  25. Emes RD, Goodstadt L, Winter EE, Ponting CP. Comparison of the genomes of human and mouse lays the foundation of genome zoology. Hum. Mol. Genet. 2003 Apr 1; 12: 701-709. [PubMed]
  26. Deng W, Liou SR, Plunkett III G, Mayhew GF, Rose DJ, Burland V, Kodoyianni V, Schwartz DC, Blattner FR. Comparative Genomics of Salmonella enterica Serovar Typhi Strains Ty2 and CT18. J Bacteriol. 2003 Apr;185(7):2330-7. [PubMed]
  27. Sasaki T, Sederoff RR. Genome studies and molecular genetics. The rice genome and comparative genomics of higher plants. Curr Opin Plant Biol. 2003 Apr;6(2):97-100. [PubMed]
  28. Ureta-Vidal A, Ettwiller L, Birney E. Comparative genomics: genome-wide analysis in metazoan eukaryotes. Nat Rev Genet. 2003 Apr;4(4):251-62. [PubMed]
  29. Satoh N. The ascidian tadpole larva: comparative molecular development and genomics. Nat Rev Genet. 2003 Apr;4(4):285-295. [PubMed]
  30. Chowdhary BP, Raudsepp T, Kata SR, Goh G, Millon LV, Allan V, Piumi F, Guerin G, Swinburne J, Binns M, Lear TL, Mickelson J, Murray J, Antczak DF, Womack JE, Skow LC. The first-generation whole-genome radiation hybrid map in the horse identifies conserved segments in human and mouse genomes. Genome Res. 2003 Apr;13(4):742-51. [PubMed][web supplement]
  31. Massey SE, Moura G, Beltrao P, Almeida R, Garey JR, Tuite MF, Santos MA. Comparative Evolutionary Genomics Unveils the Molecular Mechanism of Reassignment of the CTG Codon in Candida spp. Genome Res. 2003 Apr;13(4):544-57. [PubMed]
  32. Seda O, Sedovacute; L. New apolipoprotein A-V: comparative genomics meets metabolism. Physiol Res. 2003 Apr;52(2):141-146. [PubMed]
  33. Osterman A, Overbeek R. Missing genes in metabolic pathways: a comparative genomics approach. Curr Opin Chem Biol. 2003 Apr; 7: 157:238-251. [PubMed]
  34. Boneca IG, Reuse Hd H, Epinat JC, Pupin M, Labigne A, Moszer I. A revised annotation and comparative analysis of Helicobacter pylori genomes. Nucleic Acids Res. 2003 Mar 15;31(6):1704-14. [PubMed]
  35. Clarke B, Lambrecht M, Rhee SY. Arabidopsis genomic information for interpreting wheat EST sequences. Funct Integr Genomics. 2003 Mar;3(1-2):33-8. [PubMed]
  36. Frazer KA, Chen X, Hinds DA, Pant PV, Patil N, Cox DR. Genomic DNA insertions and deletions occur frequently between humans and nonhuman primates. Genome Res. 2003 Mar;13(3):341-6. [PubMed][web supplement]
  37. Locke DP, Segraves R, Carbone L, Archidiacono N, Albertson DG, Pinkel D, Eichler EE. Large-scale variation among human and great ape genomes determined by array comparative genomic hybridization. Genome Res. 2003 Mar;13(3):347-57. [PubMed]
  38. Liu G, Program NC, Zhao S, Bailey JA, Sahinalp SC, Alkan C, Tuzun E, Green ED, Eichler EE. Analysis of Primate Genomic Variation Reveals a Repeat-Driven Expansion of the Human Genome. Genome Res. 2003 Mar;13(3):358-368. [PubMed]
  39. Goode DK, Snell PK, Elgar GK. Comparative analysis of vertebrate Shh genes identifies novel conserved non-coding sequence. Mamm Genome. 2003 Mar;14(3):192-201. [PubMed]
  40. Woodage T, Broder S. The human genome and comparative genomics: understanding human evolution, biology, and medicine. J Gastroenterol. 2003 Mar;38 Suppl 15:68-77. [PubMed]
  41. Brooks R, Williamson J, Hensley A, Butler E, Touchton G, Smith E. Buccal cells as a source of DNA for comparative animal genomic analysis. Biotechnol Lett. 2003 Mar;25(6):451-4. [PubMed]
  42. Gibbs RA, Nelson DL. Human genetics. Primate shadow play. Science. 2003 Feb 28;299(5611):1331-3. [PubMed]
    Boffelli D, McAuliffe J, Ovcharenko D, Lewis KD, Ovcharenko I, Pachter L, Rubin EM. Phylogenetic shadowing of primate sequences to find functional regions of the human genome. Science. 2003 Feb 28;299(5611):1391-4. [PubMed]
  43. Paulson L, Martin P, Persson A, Nilsson CL, Ljung E, Westman-Brinkmalm A, Eriksson PS, Blennow K, Davidsson P. Comparative genome- and proteome analysis of cerebral cortex from MK-801-treated rats. J Neurosci Res. 2003 Feb 15;71(4):526-33. [PubMed]
  44. Woram RA, Gharbi K, Sakamoto T, Hoyheim B, Holm LE, Naish K, McGowan C, Ferguson MM, Phillips RB, Stein J, Guyomard R, Cairney M, Taggart JB, Powell R, Davidson W, Danzmann RG. Comparative genome analysis of the primary sex-determining locus in salmonid fishes. Genome Res. 2003 Feb;13(2):272-80. [PubMed]
  45. Kessler MM, Zeng Q, Hogan S, Cook R, Morales AJ, Cottarel G. Systematic Discovery of New Genes in the Saccharomyces cerevisiae Genome. Genome Res. 2003 Feb;13(2):264-71. [PubMed]
  46. Chastanet A, Fert J, Msadek T. Comparative genomics reveal novel heat shock regulatory mechanisms in Staphylococcus aureus and other Gram-positive bacteria. Mol Microbiol. 2003 Feb;47(4):1061-73. [PubMed]
  47. Wong S, Fares MA, Zimmermann W, Butler G, Wolfe KH. Evidence from comparative genomics for a complete sexual cycle in the 'asexual' pathogenic yeast Candida glabrata. Genome Biol 2003 Feb; 4(2):R10.[PubMed][pdf]
  48. Thomas JW, Touchman JW. Vertebrate genome sequencing: building a backbone for comparative genomics. Trends Genet. 2002 Feb;18(2):104-8. [PubMed]
  49. Hughes AL. Comparative Genomics: Genomes of mice and men. Heredity. 2003 Feb;90(2):115-7. [PubMed]
  50. Gibson G. Comparative genomics: Population genomics: celebrating individual expression. Heredity. 2003 Jan;90(1):1-2. [PubMed]
  51. Archibald JM, Keeling PJ. Comparative genomics: Plant genomes: cyanobacterial genes revealed. Heredity. 2003 Jan;90(1):2-3. [PubMed]
  52. Lenhard B, Sandelin A, Mendoza L, Engstrom P, Jareborg N, Wasserman WW. Identification of conserved regulatory elements by comparative genome analysis. J Biol. 2003 [epub ahead of print] [PubMed]
  53. Fay JC, Wu CI. Sequence divergence, functional constraint, and selection in protein evolution. Annu Rev Genomics Hum Genet. 2003;4:213-35. [PubMed]
  54. <>Jaillon O, Aury JM, Roest Crollius H, Salanoubat M, Wincker P, Dossat C, Castelli V, Boudet N, Samair S, Eckenberg R, Bonneval S, Saurin W, Scarpelli C, Schachter V, Weissenbach J. Genome-wide analyses based on comparative genomics. Cold Spring Harb Symp Quant Biol. 2003;68:275-82. [PubMed]
  55. <>Pennacchio LA, Baroukh N, Rubin EM. Human-mouse comparative genomics: successes and failures to reveal functional regions of the human genome. Cold Spring Harb Symp Quant Biol. 2003;68:303-9. [PubMed]

Population Genomics/Evolutionary Genomics

  1. Eisen JA, Fraser CM. Phylogenomics: intersection of evolution and genomics. Science. 2003 Jun 13;300(5626):1706-7. [PubMed]
  2. Elena SF, Lenski RE. Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation. Nat Rev Genet. 2003 Jun;4(6):457-69. [PubMed]
  3. van der Meer JR, Sentchilo V.  Genomic islands and the evolution of catabolic pathways in bacteria. Curr Opin Biotechnol. 2003 Jun;14(3):248-54.  [PubMed]
  4. Marin I. Evolution of chromatin-remodeling complexes: comparative genomics reveals the ancient origin of "Novel" compensasome genes. J Mol Evol. 2003 May;56(5):527-39. [PubMed]
  5. Akhunov ED, Goodyear AW, Geng S, Qi LL, Echalier B, Gill BS, Miftahudin, Gustafson JP, Lazo G, Chao S, Anderson OD, Linkiewicz AM, Dubcovsky J, Rota ML, Sorrells ME, Zhang D, Nguyen HT, Kalavacharla V, Hossain K, Kianian SF, Peng J, Lapitan NL, Gonzalez-Hernandez JL, Anderson JA, Choi DW, Close TJ, Dilbirligi M, Gill KS, Walker-Simmons MK, Steber C, McGuire PE, Qualset CO, Dvorak J. The organization and rate of evolution of wheat genomes are correlated with recombination rates along chromosome arms. Genome Res. 2003 May;13(5):753-63. [PubMed]
  6. Neafsey DE, Palumbi SR. Genome size evolution in pufferfish: a comparative analysis of diodontid and tetraodontid pufferfish genomes. Genome Res. 2003 May;13(5):821-30. [PubMed]
  7. Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, De La Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, Giacomini KM, Pharmacogenetics Of Membrane Transporters Investigators. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci U S A. 2003 Apr 28 [epub ahead of print] [PubMed][pdf]
  8. Carroll SB. Genetics and the making of Homo sapiens. Nature. 2003 Apr 24;422(6934):849-57. [PubMed]
  9. Hampson S, McLysaght A, Gaut B, Baldi P. LineUp: Statistical Detection of Chromosomal Homology With Application to Plant Comparative Genomics. Genome Res. 2003 Apr 14 [epub ahead of print] [PubMed]
  10. Joy DA, Feng X, Mu J, Furuya T, Chotivanich K, Krettli AU, Ho M, Wang A, White NJ, Suh E, Beerli P, Su XZ. Early Origin and Recent Expansion of Plasmodium falciparum. Science. 2003 Apr 11;300(5617):318-21. [PubMed][web supplement]
  11. Rieseberg LH, Livingstone K. EVOLUTION: Chromosomal Speciation in Primates. Science. 2003 Apr 11;300(5617):267-8. [PubMed]
  12. Navarro A, Barton NH. Chromosomal speciation and molecular divergence--accelerated evolution in rearranged chromosomes. Science. 2003 Apr 11;300(5617):321-4. [PubMed][web supplement]
  13. Zhivotovsky LA, Rosenberg NA, Feldman MW. Features of Evolution and Expansion of Modern Humans, Inferred from Genomewide Microsatellite Markers. Am J Hum Genet. 2003 Apr 10 [epub ahead of print] [PubMed]
  14. Hayes BJ, Visscher PM, McPartlan HC, Goddard ME. Novel multilocus measure of linkage disequilibrium to estimate past effective population size. Genome Res. 2003 Apr;13(4):635-43. [PubMed]
  15. Massey SE, Moura G, Beltrao P, Almeida R, Garey JR, Tuite MF, Santos MA. Comparative Evolutionary Genomics Unveils the Molecular Mechanism of Reassignment of the CTG Codon in Candida spp. Genome Res. 2003 Apr;13(4):544-57. [PubMed]
  16. Danchin A. Genomes and evolution. Curr Issues Mol Biol. 2003 Apr;5(2):37-42. [PubMed]
  17. Kellogg EA. Genome evolution: It's all relative. Nature. 2003 Mar 27;422(6930):383-4. [PubMed]
  18. Bowers JE, Chapman BA, Rong J, Paterson AH. Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events. Nature. 2003 Mar 27;422(6930):433-8. [PubMed]
  19. Wolfe KH, Li WH. Molecular evolution meets the genomics revolution. Nat Genet. 2003 Mar;33 Suppl:255-65. [PubMed]
  20. Cavalli-Sforza LL, Feldman MW. The application of molecular genetic approaches to the study of human evolution. Nat Genet. 2003 Mar;33 Suppl:266-75. [PubMed]
  21. Wooding S. PopHist: inferring population history from the spectrum of allele frequencies. Bioinformatics 2003 Mar; 19: 539-540. [PubMed]
  22. Wilson GA, Rannala B. Bayesian inference of recent migration rates using multilocus genotypes. Genetics. 2003 Mar;163(3):1177-91. [PubMed]
  23. Marth G, Schuler G, Yeh R, Davenport R, Agarwala R, Church D, Wheelan S, Baker J, Ward M, Kholodov M, Phan L, Czabarka E, Murvai J, Cutler D, Wooding S, Rogers A, Chakravarti A, Harpending HC, Kwok PY, Sherry ST. Sequence variations in the public human genome data reflect a bottlenecked population history. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):376-381. [PubMed][web supplement]
  24. Gibson G. Comparative genomics: Population genomics: celebrating individual expression. Heredity. 2003 Jan;90(1):1-2. [PubMed]

Behavioral Genomics (Behaviomics? :))

  1. Hofmann HA. Functional genomics of neural and behavioral plasticity. J Neurobiol. 2003 Jan;54(1):272-82. [PubMed]

Network/pathway reconstruction and analysis

  1. Isaacs FJ, Hasty J, Cantor CR, Collins JJ. Prediction and measurement of an autoregulatory genetic module. Proc Natl Acad Sci U S A. 2003 Jun 13 [Epub ahead of print] [PubMed][pdf] 
  2. Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Gor V, Goryanin II, Hedley WJ, Hodgman TC, Hofmeyr JH, Hunter PJ, Juty NS, Kasberger JL, Kremling A, Kummer U, Le Novere N, Loew LM, Lucio D, Mendes P, Minch E, Mjolsness ED, Nakayama Y, Nelson MR, Nielsen PF, Sakurada T, Schaff JC, Shapiro BE, Shimizu TS, Spence HD, Stelling J, Takahashi K, Tomita M, Wagner J, Wang J. The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics 2003 Mar; 19: 524-531. [PubMed]
  3. Aburatani S, Tashiro K, Savoie CJ, Nishizawa M, Hayashi K, Ito Y, Muta S, Yamamoto K, Ogawa M, Enomoto A, Masaki M, Watanabe S, Maki Y, Takahashi Y, Eguchi Y, Sakaki Y, Kuhara S. Discovery of novel transcription control relationships with gene regulatory networks generated from multiple-disruption full genome expression libraries. DNA Res. 2003 Feb 28;10(1):1-8. [PubMed]
  4. Madan Babu M, Teichmann SA. Evolution of transcription factors and the gene regulatory network in Escherichia coli. Nucleic Acids Res. 2003 Feb 15;31(4):1234-44. [PubMed]

Metabolomics

  1. Steuer R, Kurths J, Fiehn O, Weckwerth W. Observing and interpreting correlations in metabolomic networks. Bioinformatics. 2003 May 22;19(8):1019-26. [PubMed]
  2. Hellerstein MK. In Vivo Measurement of Fluxes through Metabolic Pathways: The Missing Link in Functional Genomics and Pharmaceutical Research. Annu Rev Nutr. 2003 Apr 16 [epub ahead of print] [PubMed]
  3. Stitt M. et al., From measurements of metabolites to metabolomics: an `on the fly' perspective illustrated by recent studies of carbon–nitrogen interactions. Curr Opin Biotechnol. 2003 Apr; 14:136-144. [PubMed]
  4. Verdonk JC, Ric de Vos CH, Verhoeven HA, Haring MA, van Tunen AJ, Schuurink RC. Regulation of floral scent production in petunia revealed by targeted metabolomics. Phytochemistry. 2003 Mar;62(6):997-1008. [PubMed]
  5. Sumner LW, Mendes P, Dixon RA. Plant metabolomics: large-scale phytochemistry in the functional genomics era. Phytochemistry. 2003 Mar;62(6):817-36. [PubMed]
  6. Griffin JL, Pole JC, Nicholson JK, Carmichael PL. Cellular environment of metabolites and a metabonomic study of tamoxifen in endometrial cells using gradient high resolution magic angle spinning 1H NMR spectroscopy. Biochim Biophys Acta. 2003 Jan 20;1619(2):151-158. [PubMed]

Pharmacogenomics

  1. Moldrup C. Ethical, social and legal implications of pharmacogenomics: a critical review. Community Genet. 2002 Jun;4(4):204-14. [PubMed]
  2. Miesel L, Greene J, Black TA. Microbial genetics: Genetic strategies for antibacterial drug discovery. Nat Rev Genet. 2003 Jun;4(6):442-56. [PubMed]
  3. Hughes D. Microbial genetics: Exploiting genomics, genetics and chemistry to combat antibiotic resistance. Nat Rev Genet. 2003 Jun;4(6):432-41. [PubMed]
  4. Kling J. US FDA contemplates collection of pharmacogenomic data. Nat Biotechnol. 2003 Jun;21(6):590. [PubMed]
  5. Hoffman EP, DuBois DC, Hoffman RI, Almon RR. Expression profiling and pharmacogenomics of muscle and muscle disease. Curr Opin Pharmacol. 2003 Jun;3(3):309-16. [PubMed]
  6. Muller M. Pharmacogenomics and drug response. Int J Clin Pharmacol Ther. 2003 Jun;41(6):231-40. [PubMed]
  7. Dracopoli NC. Pharmacogenomic applications in clinical drug development. Cancer Chemother Pharmacol. 2003 Jun;52 Suppl 1:57-60. [PubMed]
  8. Ellis JT, Morrison DA, Reichel MP. Genomics and its impact on parasitology and the potential for development of new parasite control methods. DNA Cell Biol. 2003 Jun;22(6):395-403. [PubMed]
  9. Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF, Kolachana B, Callicott JH, Weinberger DR. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6186-91. [PubMed][pdf]
  10. Sehgal A. Anticancer Drug Discovery using Chemical Genomics. Curr Med Chem. 2003 May;10(9):749-55. [PubMed]
  11. Neckers L. Development of small molecule hsp90 inhibitors: utilizing both forward and reverse chemical genomics for drug identification. Curr Med Chem. 2003 May;10(9):733-9. [PubMed]
  12. Kwon HJ. Chemical genomics-based target identification and validation of anti-angiogenic agents. Curr Med Chem. 2003 May;10(9):717-36. [PubMed]
  13. Evans WE. Pharmacogenomics: marshalling the human genome to individualise drug therapy. Gut. 2003 May;52 Suppl 2:II10-II18. [PubMed]
  14. Leeder JS. Developmental and pediatric pharmacogenomics. Pharmacogenomics. 2003 May;4(3):331-41. [PubMed]
  15. Brock TP, Valgus JM, Smith SR, Summers KM. Pharmacogenomics: implications and considerations for pharmacists. Pharmacogenomics. 2003 May;4(3):321-30. [PubMed]
  16. Yagil Y, Yagil C. Pharmacogenomic considerations for immunosuppressive therapy. Pharmacogenomics. 2003 May;4(3):309-19. [PubMed]
  17. Bianchi G, Staessen JA, Patrizia F. Pharmacogenomics of primary hypertension - the lessons from the past to look toward the future. Pharmacogenomics. 2003 May;4(3):279-96. [PubMed]
  18. Phillips KA, Veenstra D, Van Bebber S, Sakowski J. An introduction to cost-effectiveness and cost-benefit analysis of pharmacogenomics. Pharmacogenomics. 2003 May;4(3):231-9. [PubMed]
  19. Bleicher KH, Bohm HJ, Muller K, Alanine AI. A guide to drug discovery: Hit and lead generation: beyond high-throughput screening. Nat Rev Drug Discov. 2003 May;2(5):369-78. [PubMed] 
  20. Severino G, Chillotti C, Stochino ME, Del Zompo M. Pharmacogenomics: state of the research and perspectives in clinical application. Neurol Sci. 2003 May;24 Suppl 2:S146-8. [PubMed]
  21. Altman RB. Genetic sequence data for pharmacogenomics. Curr Opin Drug Discov Devel. 2003 May;6(3):297-303. [PubMed]
  22. Veal GJ, Coulthard SA, Boddy AV. Chemotherapy individualization. Invest New Drugs. 2003 May;21(2):149-56. [PubMed]
  23. Gant TW. Application of toxicogenomics in drug development. Drug News Perspect. 2003 May;16(4):217-21. [PubMed]
  24. Melton L. Pharmacogenetics and Genotyping: On the trail of SNPs. Nature. 2003 Apr 24;422(6934):917-23. [PubMed]
  25. Raghavan D. Molecular targeting and pharmacogenomics in the management of advanced bladder cancer. Cancer. 2003 Apr 15;97(8 Suppl):2083-9. [PubMed]
  26. Strausberg RL, Schreiber SL. From knowing to controlling: a path from genomics to drugs using small molecule probes. Science. 2003 Apr 11;300(5617):294-5. [PubMed]
  27. Pedley TA, Hirano M. Is refractory epilepsy due to genetically determined resistance to antiepileptic drugs? N Engl J Med. 2003 Apr 10;348(15):1480-2. [PubMed]
  28. Nicholls H. Improving drug response with pharmacogenomics. Drug Discov Today. 2003 Apr 1;8(7):281-2. [PubMed]
  29. Chong E, Ensom MH. Pharmacogenetics of the proton pump inhibitors: a systematic review. Pharmacotherapy. 2003 Apr;23(4):460-71. [PubMed]
  30. Sparreboom A, Danesi R, Ando Y, Chan J, Figg WD. Pharmacogenomics of ABC transporters and its role in cancer chemotherapy. Drug Resist Updat. 2003 Apr;6(2):71-84. [PubMed]
  31. Erlich H, Bonnet J, Frueh FW, Bertrand P, Schmitz G, Salvatore G, Little S, Lambert C, Baranova E, Siest G. Pharmacogenetics: from bench to bedside. Clin Chem Lab Med. 2003 Apr;41(4):610-4. [PubMed]
  32. Siest G, Ferrari L, Accaoui MJ, Batt AM, Visvikis S. Pharmacogenomics of drugs affecting the cardiovascular system. Clin Chem Lab Med. 2003 Apr;41(4):590-9. [PubMed]
  33. Schmitz G, Drobnik W. Pharmacogenomics and pharmacogenetics of cholesterol-lowering therapy. Clin Chem Lab Med. 2003 Apr;41(4):581-9. [PubMed]
  34. Oscarson M. Pharmacogenetics of drug metabolising enzymes: importance for personalised medicine. Clin Chem Lab Med. 2003 Apr;41(4):573-80. [PubMed]
  35. Boissel JP, Gueyffier F, Cucherat M, Bricca G. Pharmacogenetics and responders to a therapy: theoretical background and practical problems. Clin Chem Lab Med. 2003 Apr;41(4):564-72. [PubMed]
  36. Frueh FW, Noyer-Weidner M. The use of denaturing high-performance liquid chromatography (DHPLC) for the analysis of genetic variations: impact for diagnostics and pharmacogenetics. Clin Chem Lab Med. 2003 Apr;41(4):452-61. [PubMed]
  37. Lindpaintner K. Pharmacogenetics and pharmacogenomics in drug discovery and development: an overview. Clin Chem Lab Med. 2003 Apr;41(4):398-410. [PubMed]
  38. Schaefer BM, Caracciolo V, Frishman WH, Charney P. Gender, Ethnicity and Genetics in Cardiovascular Disease Part 1: Basic Principles. Heart Dis. 2003 Mar-Apr;5(2):129-143. [PubMed]
  39. Watters JW, McLeod HL. Cancer pharmacogenomics: current and future applications. Biochim Biophys Acta. 2003 Mar 17;1603(2):99-111. [PubMed]
  40. Gurwitz D, Weizman A, Rehavi M.  Education: Teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine. Trends Pharmacol Sci. 2003 Mar; 24: 122-125. [PubMed]
  41. Ryan SG. Regression to the truth: replication of association in pharmacogenetic studies. Pharmacogenomics. 2003 Mar;4(2):201-7. [PubMed]
  42. Rudnicki M, Mayer G. Pharmacogenomics of angiotensin converting enzyme inhibitors in renal disease - pathophysiological considerations. Pharmacogenomics. 2003 Mar;4(2):153-62. [PubMed]
  43. Danesi R, De Braud F, Fogli S, De Pas TM, Di Paolo A, Curigliano G, Del Tacca M. Pharmacogenetics of anticancer drug sensitivity in non-small cell lung cancer. Pharmacol Rev. 2003 Mar;55(1):57-103. [PubMed]
  44. Tsongalis GJ, Ricci A. Breast cancer as a model of realistic challenges in pharmacogenomics. Clin Biochem. 2003 Mar;36(2):89-94. [PubMed]
  45. Meisel C, Gerloff T, Kirchheiner J, Mrozikiewicz PM, Niewinski P, Brockmoller J, Roots I. Implications of pharmacogenetics for individualizing drug treatment and for study design. J Mol Med. 2003 Mar;81(3):154-67. [PubMed]
  46. Lindpaintner K. Pharmacogenetics and the future of medical practice. J Mol Med. 2003 Mar;81(3):141-53. [PubMed]
  47. Baliga RR, Narula J. Pharmacogenomics of congestive heart failure. Med Clin North Am. 2003 Mar;87(2):569-78, xiv. [PubMed]
  48. Dewar JC, Hall IP. Personalised prescribing for asthma - is pharmacogenetics the answer? J Pharm Pharmacol. 2003 Mar;55(3):279-89. [PubMed]
  49. Norbert PW, Roses AD. Pharmacogenetics and pharmacogenomics: recent developments, their clinical relevance and some ethical, social, and legal implications. J Mol Med. 2003 Mar;81(3):135-40. [PubMed]
  50. Chanda SK, Caldwell JS. Fulfilling the promise: drug discovery in the post-genomic era. Drug Discov Today. 2003 Feb 15;8(4):168-74. [PubMed]
  51. Davidov E, Holland J, Marple E, Naylor S. Advancing drug discovery through systems biology. Drug Discov Today. 2003 Feb 15;8(4):175-83. [PubMed]
  52. Goldstein DB. Pharmacogenetics in the laboratory and the clinic. N Engl J Med. 2003 Feb 6;348(6):553-6. [PubMed]
  53. Evans WE, McLeod HL. Pharmacogenomics--drug disposition, drug targets, and side effects. N Engl J Med. 2003 Feb 6;348(6):538-49. [PubMed]
  54. Weinshilboum R. Inheritance and drug response. N Engl J Med. 2003 Feb 6;348(6):529-37. [PubMed]
  55. Taylor PW, Stapleton PD. Structural pharmacogenomics: the answer to antimicrobial drug resistance? Drug Discov Today. 2003 Feb 1;8(3):110-1. [PubMed]
  56. Sherrid P. Is there a market for personal medicine? US News World Rep. 2003 Jan 20;134(2):56. [PubMed]
    Fischman J. On target. A new generation of drugs offers customized cures. US News World Rep. 2003 Jan 20;134(2):50-2, 55-6, 58. [PubMed]
  57. Cadman PE, O'Connor DT. Pharmacogenomics of hypertension. Curr Opin Nephrol Hypertens. 2003 Jan;12(1):61-70. [PubMed]
  58. Tafti M, Dauvilliers Y. Pharmacogenomics in the treatment of narcolepsy. Pharmacogenomics. 2003 Jan;4(1):23-33. [PubMed]
  59. O'Kane DJ, Weinshilboum RM, Moyer TP. Pharmacogenomics and reducing the frequency of adverse drug events. Pharmacogenomics. 2003 Jan;4(1):1-4. [PubMed]
  60. Anderson JL, Carlquist JF, Horne BD, Muhlestein JB. Cardiovascular pharmacogenomics: current status, future prospects. J Cardiovasc Pharmacol Ther. 2003 Jan;8(1):71-83. [PubMed]
  61. Witzmann FA, Grant RA. Pharmacoproteomics in drug development. Pharmacogenomics J. 2003;3(2):69-76. [PubMed]
  62. Binzak BA. How pharmacogenomics will impact the federal regulation of clinical trials and the new drug approval process. Food Drug Law J. 2003;58(1):103-27. [PubMed]
  63. Meunier JC. Utilizing functional genomics to identify new pain treatments : the example of nociceptin. Am J Pharmacogenomics. 2003;3(2):117-30. [PubMed]
  64. Yan Q. Pharmacogenomics of membrane transporters an overview. Methods Mol Biol. 2003;227:1-20. [PubMed]
  65. Guillemette C. Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharmacogenomics J. 2003;3(3):136-58. [PubMed]
  66. McLeod HL, Yu J. Cancer pharmacogenomics: SNPs, chips, and the individual patient. Cancer Invest. 2003;21(4):630-40. [PubMed]
  67. Patarca R, Isava A, Campo R, Rodriguez NJ, Nunez E, Alter M, Marchette M, Sanabia MM, Mitchell C, Rivera D, Scott G, Jayaweera D, Moreno J, Boulanger C, Kolber M, Mask CW, Sierra EM, Vallejo R, Page JB, Klimas NG, Fletcher MA. Human immunodeficiency virus type 1 pharmacogenomics in clinical practice: relevance of HIV-1 drug resistance testing (Part 1). J Environ Pathol Toxicol Oncol. 2003;22(3):201-34. [PubMed]

Toxicogenomics

  1. Ballatori N, Boyer JL, Rockett JC. Exploiting genome data to understand the function, regulation, and evolutionary origins of toxicologically relevant genes sequences. Environ Health Perspect. 2003 May;111(6):871-5. [PubMed]
  2. Orphanides G. Toxicogenomics: challenges and opportunities. Toxicol Lett. 2003 Apr 11;140-141:145-8. [PubMed]
  3. Lehmann J. Toxicogenomics takes center stage. Drug News Perspect. 2003 Apr;16(3):183-6. [PubMed]
  4. Tugwood JD, Hollins LE, Cockerill MJ. Genomics and the search for novel biomarkers in toxicology. Biomarkers. 2003 Mar-Apr;8(2):79-92. [PubMed]
  5. Heijne WH, Stierum RH, Slijper M, van Bladeren PJ, van Ommen B. Toxicogenomics of bromobenzene hepatotoxicity: a combined transcriptomics and proteomics approach. Biochem Pharmacol. 2003 Mar 1;65(5):857-75. [PubMed]
  6. Salter AH, Nilsson KC. Informatics and multivariate analysis of toxicogenomics data. Curr Opin Drug Discov Devel. 2003 Jan;6(1):117-22. [PubMed]
  7. Waters M, Boorman G, Bushel P, Cunningham M, Irwin R, Merrick A, Olden K, Paules R, Selkirk J, Stasiewicz S, Weis B, Van Houten B, Walker N, Tennant R. Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base. EHP Toxicogenomics. 2003 Jan;111(1T):15-28. [PubMed]
  8. Ballatori N, Boyer JL, Rockett JC. Exploiting genome data to understand the function, regulation, and evolutionary origins of toxicologically relevant genes. EHP Toxicogenomics. 2003 Jan;111(1T):61-5. [PubMed]
  9. Schmidt CW. Toxicogenomics. An emerging discipline. EHP Toxicogenomics. 2003 Jan;111(1T):A20-5. [PubMed]
  10. Selkirk JK. National Center for Toxicogenomics: an introduction. EHP Toxicogenomics. 2003 Jan;111(1T):A18-9. [PubMed]

System Biology

  1. Selinger DW, Wright MA, Church GM. On the complete determination of biological systems. Trends Biotechnol. 2003 Jun;21(6):251-4.  [PubMed]
  2. Katagiri F. Attacking complex problems with the power of systems biology. Plant Physiol. 2003 Jun;132(2):417-9. [PubMed]
  3. Shasha DE. Plant systems biology: lessons from a fruitful collaboration. Plant Physiol. 2003 Jun;132(2):415-6. [PubMed]
  4. Raikhel NV, Coruzzi GM. Plant systems biology. Plant Physiol. 2003 Jun;132(2):403. [PubMed]
  5. Raikhel NV, Coruzzi GM. Achieving the in silico plant. Systems biology and the future of plant biological research. Plant Physiol. 2003 Jun;132(2):404-9. [PubMed]
  6. Carney SL. Leroy Hood expounds the principles, practice and future of systems biology. Drug Discov Today. 2003 May 15;8(10):436-8. [PubMed]
  7. Aitchison JD, Galitski T. Inventories to insights. J Cell Biol. 2003 May 12;161(3):465-9. [PubMed]
  8. Rangel-Aldao R. Developing countries and systems biology. Nat Biotechnol. 2003 May;21(5):491-2. [PubMed]
  9. Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Gor V, Goryanin II, Hedley WJ, Hodgman TC, Hofmeyr JH, Hunter PJ, Juty NS, Kasberger JL, Kremling A, Kummer U, Le Novere N, Loew LM, Lucio D, Mendes P, Minch E, Mjolsness ED, Nakayama Y, Nelson MR, Nielsen PF, Sakurada T, Schaff JC, Shapiro BE, Shimizu TS, Spence HD, Stelling J, Takahashi K, Tomita M, Wagner J, Wang J. The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics 2003 Mar; 19: 524-531. [PubMed]
  10. Davidov E, Holland J, Marple E, Naylor S. Advancing drug discovery through systems biology. Drug Discov Today. 2003 Feb 15;8(4):175-83. [PubMed]
  11. Steven Wiley H, Shvartsman SY, Lauffenburger DA. Computational modeling of the EGF-receptor system: a paradigm for systems biology. Trends Cell Biol. 2003 Jan;13(1):43-50. [PubMed]
  12. Hood L. Systems biology: integrating technology, biology, and computation. Mech Ageing Dev. 2003 Jan;124(1):9-16. [PubMed]

Database

Nucleic Acid Research January 1, 2003 issue - The Molecular Biology Database Collection - The link to the complete issue

Applications

  1. Ben-Shlomo I, Yu Hsu S, Rauch R, Kowalski HW, Hsueh AJ. Signaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction. Sci STKE. 2003 Jun 17;2003(187):RE9. [PubMed]
  2. Allen J, Davey HM, Broadhurst D, Heald JK, Rowland JJ, Oliver SG, Kell DB. High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nat Biotechnol. 2003 Jun;21(6):692-6. [PubMed][web supplement]
  3. Valenzuela DM, Murphy AJ, Frendewey D, Gale NW, Economides AN, Auerbach W, Poueymirou WT, Adams NC, Rojas J, Yasenchak J, Chernomorsky R, Boucher M, Elsasser AL, Esau L, Zheng J, Griffiths JA, Wang X, Su H, Xue Y, Dominguez MG, Noguera I, Torres R, Macdonald LE, Stewart AF, DeChiara TM, Yancopoulos GD. High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat Biotechnol. 2003 Jun;21(6):652-9. [PubMed][web supplement]
  4. Strausberg RL, Simpson AJ, Wooster R. Sequence-based cancer genomics: progress, lessons and opportunities. Nat Rev Genet. 2003 Jun;4(6):409-18. [PubMed]
  5. Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol. 2003 Jun;21(6):635-7. [PubMed][web supplement]
  6. Scholl EH. et al., Horizontally transferred genes in plant-parasitic nematodes: a high-throughput genomic approach. Genome Biol 2003 Jun; [PubMed]
  7. González V. et al., The mosaic structure of the symbiotic plasmid of Rhizobium etli CFN42 and its relation to other symbiotic genome compartments. Genome Biol 2003 Jun; [PubMed]
  8. Han W, Ding P, Xu M, Wang L, Rui M, Shi S, Liu Y, Zheng Y, Chen Y, Yang T, Ma D. Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. Genomics. 2003 Jun;81(6):609-17. [PubMed]
  9. Rocha EP. An appraisal of the potential for illegitimate recombination in bacterial genomes and its consequences: from duplications to genome reduction. Genome Res. 2003 Jun;13(6):1123-32. [PubMed][pdf][web supplement]
  10. Kapatral V, Ivanova N, Anderson I, Reznik G, Bhattacharyya A, Gardner WL, Mikhailova N, Lapidus A, Larsen N, D'Souza M, Walunas T, Haselkorn R, Overbeek R, Kyrpides N. Genome Analysis of F. nucleatum sub spp vincentii and Its Comparison With the Genome of F. nucleatum ATCC 25586. Genome Res. 2003 Jun;13(6):1180-9. [PubMed][pdf]
  11. Zhang L, Pavlovic V, Cantor CR, Kasif S. Human-mouse gene identification by comparative evidence integration and evolutionary analysis. Genome Res. 2003 Jun;13(6):1190-202. [PubMed][pdf]
  12. Yuhki N, Beck T, Stephens RM, Nishigaki Y, Newmann K, O'Brien SJ. Comparative Genome Organization of Human, Murine, and Feline MHC Class II Region. Genome Res. 2003 Jun;13(6):1169-79. [PubMed][pdf]
  13. Inoue K, Lupski JR. Genetics and genomics of behavioral and psychiatric disorders. Curr Opin Genet Dev. 2003 Jun;13(3):303-9.  [PubMed]
  14. Jun JE. et al., Identifying the MAGUK Protein Carma-1 as a Central Regulator of Humoral Immune Responses and Atopy by Genome-Wide Mouse Mutagenesis. Immunity 2003 Jun; [PubMed]
  15. Lee JY, Lee DH. Use of serial analysis of gene expression technology to reveal changes in gene expression in Arabidopsis pollen undergoing cold stress. Plant Physiol. 2003 Jun;132(2):517-29. [PubMed]
  16. Special FANTOM2 Issue. Genome Res. 2003 Jun
  17. Schloss PD, Handelsman J. Biotechnological prospects from metagenomics. Curr Opin Biotechnol. 2003 Jun;14(3):303-10.  [PubMed]
  18. Alarcon-Riquelme ME. Functional genomics in the study of autoimmune diseases. Autoimmun Rev. 2003 Jun;2(4):177-80. [PubMed]
  19. Giudice LC. Elucidating endometrial function in the post-genomic era. Hum Reprod Update. 2003 May-Jun;9(3):223-35. [PubMed]
  20. Gaston B. Functional genomics and proteomics in control of breathing. Respir Physiol Neurobiol. 2003 May 30;135(2-3):231-8. [PubMed]
  21. Mackiewicz M, Pack AI. Functional genomics of sleep. Respir Physiol Neurobiol. 2003 May 30;135(2-3):207-20. [PubMed]
  22. Prabhakar N, Champagnat J. Functional genomics and proteomics in control of breathing. Respir Physiol Neurobiol. 2003 May 30;135(2-3):107-8. [PubMed]
  23. Bardelli A, Parsons DW, Silliman N, Ptak J, Szabo S, Saha S, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Mutational Analysis of the Tyrosine Kinome in Colorectal Cancers. Science. 2003 May 9;300(5621):949. [PubMed][web supplement]
  24. Cho-Chung YS, Becker KG. A genome-wide view of antisense. Nat Biotechnol. 2003 May;21(5):492. [PubMed]
  25. Boone C, Andrews B. ORFeomics: correcting the wiggle in worm genes. Nat Genet. 2003 May;34(1):8-9. [PubMed]
  26. Reboul J, Vaglio P, Rual JF, Lamesch P, Martinez M, Armstrong CM, Li S, Jacotot L, Bertin N, Janky R, Moore T, Hudson JR, Hartley JL, Brasch MA, Vandenhaute J, Boulton S, Endress GA, Jenna S, Chevet E, Papasotiropoulos V, Tolias PP, Ptacek J, Snyder M, Huang R, Chance MR, Lee H, Doucette-Stamm L, Hill DE, Vidal M. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Nat Genet 2003 May;34(1):35-41 [PubMed][web supplement]
  27. Barrans JD, Ip J, Lam CW, Hwang IL, Dzau VJ, Liew CC. Chromosomal distribution of the human cardiovascular transcriptome. Genomics. 2003 May; 81: 519-524. [PubMed]
  28. Sapone A, Vaira D, Trespidi S, Perna F, Gatta L, Tampieri A, Ricci C, Cantelli-Forti G, Miglioli M, Biagi GL, Paolini M. The clinical role of cytochrome p450 genotypes in Helicobacter pylori management. Am J Gastroenterol. 2003 May;98(5):1010-5. [PubMed]
  29. Friedberg EC, Fischhaber PL. TB or Not TB. How Mycobacterium tuberculosis May Evade Drug Treatment. Cell. 2003 Apr 18;113(2):139-40. [PubMed]
  30. Kobayashi K, Ehrlich SD, Albertini A, Amati G, Andersen KK, Arnaud M, Asai K, Ashikaga S, Aymerich S, Bessieres P, Boland F, Brignell SC, Bron S, Bunai K, Chapuis J, Christiansen LC, Danchin A, Debarbouille M, Dervyn E, Deuerling E, Devine K, Devine SK, Dreesen O, Errington J, Fillinger S, Foster SJ, Fujita Y, Galizzi A, Gardan R, Eschevins C, Fukushima T, Haga K, Harwood CR, Hecker M, Hosoya D, Hullo MF, Kakeshita H, Karamata D, Kasahara Y, Kawamura F, Koga K, Koski P, Kuwana R, Imamura D, Ishimaru M, Ishikawa S, Ishio I, Le Coq D, Masson A, Mauel C, Meima R, Mellado RP, Moir A, Moriya S, Nagakawa E, Nanamiya H, Nakai S, Nygaard P, Ogura M, Ohanan T, O'Reilly M, O'Rourke M, Pragai Z, Pooley HM, Rapoport G, Rawlins JP, Rivas LA, Rivolta C, Sadaie A, Sadaie Y, Sarvas M, Sato T, Saxild HH, Scanlan E, Schumann W, Seegers JF, Sekiguchi J, Sekowska A, Seror SJ, Simon M, Stragier P, Studer R, Takamatsu H, Tanaka T, Takeuchi M, Thomaides HB, Vagner V, Van Dijl JM, Watabe K, Wipat A, Yamamoto H, Yamamoto M, Yamamoto Y, Yamane K, Yata K, Yoshida K, Yoshikawa H, Zuber U, Ogasawara N. Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4678-83. [PubMed][pdf][web supplement]
  31. Fernandez PC, Frank SR, Wang L, Schroeder M, Liu S, Greene J, Cocito A, Amati B. Genomic targets of the human c-Myc protein. Genes Dev. 2003 Apr 14 [epub ahead of print] [PubMed]
  32. Serikawa KA, Xu XL, MacKay VL, Law GL, Zong Q, Zhao LP, Bumgarrner R, Morris DR. The transcriptome and its translation during recovery from cell-cycle arrest in Saccharomyces cerevisiae. Mol Cell Proteomics. 2003 Apr 7 [epub ahead of print] [PubMed]
  33. Carmichael GG. Antisense starts making more sense. Nat Biotechnol. 2003 Apr;21(4):371-2. [PubMed]
  34. Yelin R, Dahary D, Sorek R, Levanon EY, Goldstein O, Shoshan A, Diber A, Biton S, Tamir Y, Khosravi R, Nemzer S, Pinner E, Walach S, Bernstein J, Savitsky K, Rotman G. Widespread occurrence of antisense transcription in the human genome. Nat Biotechnol. 2003 Apr;21(4):379-86. [PubMed][web supplement]
  35. Koncz C.  Plant biotechnology: From genome projects to molecular breeding. Curr Opin Biotechnol. 2003 Apr; 14:133-135. [PubMed]
  36. Weidner S, Puhler A, Kuster H. Genomics insights into symbiotic nitrogen fixation. Curr Opin Biotechnol. 2003 Apr; 14:200-205. [PubMed]
  37. Bhalerao R, Nilsson O, Sandberg G. Out of the woods: forest biotechnology enters the genomic era. Curr Opin Biotechnol. 2003 Apr; 14:206-213. [PubMed]
  38. Morgante M. et al., From plant genomics to breeding practice. Curr Opin Biotechnol. 2003 Apr; 14:214-219. [PubMed]
  39. Hofmann G, McIntyre M, Nielsen J. Fungal genomics beyond Saccharomyces cerevisiae? Curr Opin Biotechnol. 2003 Apr; 14:226-231. [PubMed]
  40. Kuiper HA, Kok EJ, Engel KH. Exploitation of molecular profiling techniques for GM food safety assessment. Curr Opin Biotechnol. 2003 Apr; 14:238-243. [PubMed]
  41. Couzin J. RNA interference. New screen nets 'Hedgehog' genes. Science. 2003 Mar 28;299(5615):1961. [PubMed]
    Lum L, Yao S, Mozer B, Rovescalli A, Von Kessler D, Nirenberg M, Beachy PA. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science. 2003 Mar 28;299(5615):2039-45. [PubMed]
  42. Zewail A, Xie MW, Xing Y, Lin L, Zhang PF, Zou W, Saxe JP, Huang J. Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3345-50. [PubMed][pdf][web supplement]
  43. Appels R, Francki M, Chibbar R. Advances in cereal functional genomics. Funct Integr Genomics. 2003 Mar;3(1-2):1-24. [