My complex disease trait mapping, genome mapping, linkage analysis journal watch - year 2002 [ this week | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 ]


General
Linkage & whole genome mapping
Sibpair
Linkage disequilibrium
Quantitative Trait Loci (QTL)
Theoretical development
Software
Database
Genetic map development
 

 Can't find the complex disease trait mapping, genome mapping or linkage analysis article published in 2002 in my site?
Try a Google search!
Google


General
  1. Glazier AM, Nadeau JH, Aitman TJ. Finding Genes That Underlie Complex Traits. Science. 2002 Dec 20;298(5602):2345-2349. [PubMed][web supplement]
  2. King MC, Motulsky AG. HUMAN GENETICS: Mapping Human History. Science. 2002 Dec 20;298(5602):2342-3. [PubMed]
  3. Rosenberg NA, Pritchard JK, Weber JL, Cann HM, Kidd KK, Zhivotovsky LA, Feldman MW. Genetic Structure of Human Populations. Science. 2002 Dec 20;298(5602):2381-2385. [PubMed][web supplement]
  4. Sankar P, Cho MK. GENETICS: Enhanced: Toward a New Vocabulary of Human Genetic Variation. Science. 2002 Nov 15;298(5597):1337-8. [PubMed]
  5. Kell DB. Genotype-phenotype mapping: genes as computer programs. Trends Genet. 2002 Nov;18(11):555-9. [PubMed]
  6. Sham P, Bader JS, Craig I, O'Donovan M, Owen M. DNA Pooling: a tool for large-scale association studies. Nat Rev Genet. 2002 Nov;3(11):862-71. [PubMed]
  7. Baldini A. DiGeorge syndrome: the use of model organisms to dissect complex genetics. Hum Mol Genet. 2002 Oct 1;11(20):2363-9. [PubMed]
  8. Fisher SE, DeFries JC. Developmental dyslexia: genetic dissection of a complex cognitive trait. Nat Rev Neurosci. 2002 Oct;3(10):767-80. [PubMed]
  9. Yan H, Yuan W, Velculescu VE, Vogelstein B, Kinzler KW. Allelic variation in human gene expression. Science. 2002 Aug 16;297(5584):1143. [PubMed][web supplement]
  10. Lyons P. Gene-expression profiling and the genetic dissection of complex disease. Curr Opin Immunol. 2002 Oct;14(5):627. [PubMed]
  11. Gill RT, Wildt S, Yang YT, Ziesman S, Stephanopoulos G. Genome-wide screening for trait conferring genes using DNA microarrays. Proc Natl Acad Sci U S A 2002 May 14;99(10):7033-7038 [PubMed][pdf]
  12. Rasmuson M. The genotype-phenotype link. Hereditas. 2002;136(1):1-6. [PubMed]
  13. Campbell H, Rudan I. Interpretation of genetic association studies in complex disease. Pharmacogenomics J. 2002;2(6):349-60. [PubMed]
Linkage & whole genome mapping
  1. Bonnen PE, Wang PJ, Kimmel M, Chakraborty R, Nelson DL. Haplotype and linkage disequilibrium architecture for human cancer-associated genes. Genome Res. 2002 Dec;12(12):1846-53. [PubMed][web supplement]
  2. Haines JL, Bradford Y, Garcia ME, Reed AD, Neumeister E, Pericak-Vance MA, Rimmler JB, Menold MM, Martin ER, Oksenberg JR, Barcellos LF, Lincoln R,Hauser SL. Multiple susceptibility loci for multiple sclerosis. Hum Mol Genet. 2002 Sep 15; 11: 2251-2256. [PubMed]
  3. Saarela J, Schoenberg Fejzo M, Chen D, Finnila S, Parkkonen M, Kuokkanen S, Sobel E, Tienari PJ, Sumelahti ML, Wikstrom J, Elovaara I, Koivisto K, Pirttila T, Reunanen M, Palotie A, Peltonen L. Fine mapping of a multiple sclerosis locus to 2.5 Mb on chromosome 17q22–q24.  Hum Mol Genet. 2002 Sep 15; 11: 2257-2267. [PubMed]
  4. Feng BJ, Huang W, Shugart YY, Lee MK, Zhang F, Xia JC, Wang HY, Huang TB, Jian SW, Huang P, Feng QS, Huang LX, Yu XJ, Li D, Chen LZ, Jia WH, Fang Y, Huang HM, Zhu JL, Liu XM, Zhao Y, Liu WQ, Deng MQ, Hu WH, Wu SX, Mo HY, Hong MF, King MC, Chen Z, Zeng YX. Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4. Nat Genet. 2002 Aug;31(4):395-9. [PubMed]
  5. Lee JK, Park C, Kimm K, Rutherford MS. Genome-wide multilocus analysis for immune-mediated complex diseases. Biochem Biophys Res Commun. 2002 Jul 26;295(4):771-3. [PubMed]
  6. Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Braunschweiger K, Walsh A, Liu Z, Hayward B, Folz C, Manning SP, Bawa A, Saracino L, Thackston M, Benchekroun Y, Capparell N, Wang M, Adair R, Feng Y, Dubois J, FitzGerald MG, Huang H, Gibson R, Allen KM, Pedan A, Danzig MR, Umland SP, Egan RW, Cuss FM, Rorke S, Clough JB, Holloway JW, Holgate ST, Keith TP. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature. 2002 Jul 25;418(6896):426-30. [PubMed][web supplement]
  7. Labuda D, Krajinovic M, Sabbagh A, Infante-Rivard C, Sinnett D. Parental Genotypes in the Risk of a Complex Disease. Am J Hum Genet 2002 Jul;71(1):193-7[PubMed]
  8. Sawa A, Snyder SH. Schizophrenia: diverse approaches to a complex disease. Science. 2002 Apr 26;296(5568):692-5. [PubMed]
  9. Kiberstis P, Roberts L. It's Not Just the Genes. Science. 2002 Apr 26;296(5568):685 [PubMed]
  10. Marx J. Unraveling the Causes of Diabetes. Science. 2002 Apr 26;296(5568):686-9. [PubMed]
  11. Marshall E. Lupus: Mysterious Disease Holds Its Secrets Tight. Science. 2002 Apr 26;296(5568):689-91. [PubMed]
  12. Willett WC. Balancing life-style and genomics research for disease prevention. Science. 2002 Apr 26;296(5568):695-8. [PubMed]
  13. Rees J. Complex disease and the new clinical sciences. Science. 2002 Apr 26;296(5568):698-700. [PubMed]
  14. Strohman R. Maneuvering in the complex path from genotype to phenotype. Science. 2002 Apr 26;296(5568):701-3. [PubMed]
  15. Levinson DF, Holmans PA, Laurent C, Riley B, Pulver AE, Gejman PV, Schwab SG, Williams NM, Owen MJ, Wildenauer DB, Sanders AR, Nestadt G, Mowry BJ, Wormley B, Bauche S, Soubigou S, Ribble R, Nertney DA, Liang KY, Martinolich L, Maier W, Norton N, Williams H, Albus M, Carpenter EB, DeMarchi N, Ewen-White KR, Walsh D, Jay M, Deleuze JF, O'Neill FA, Papadimitriou G, Weilbaecher A, Lerer B, O'Donovan MC, Dikeos D, Silverman JM, Kendler KS, Mallet J, Crowe RR, Walters M. No Major Schizophrenia Locus Detected on Chromosome 1q in a Large Multicenter Sample.  Science. 2002 Apr 26;296(5568):739-741.[PubMed][web supplement]
  16. Liu H, Heath SC, Sobin C, Roos JL, Galke BL, Blundell ML, Lenane M, Robertson B, Wijsman EM, Rapoport JL, Gogos JA, Karayiorgou M. Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3717-3722. [PubMed][pdf][web supplement]
  17. Philippe A, Guilloud-Bataille M, Martinez M, Gillberg C, Rastam M, Sponheim E, Coleman M, Zappella M, Aschauer H, Penet C, Feingold J, Brice A, Leboyer M. Analysis of ten candidate genes in autism by association and linkage. Am J Med Genet. 2002 Mar 8; 114:125-128 [PubMed]
  18. Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Knowles H, Morris JC, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, Rice F, Giles P, Tunstall N, Jones L, Lovestone S, Williams J, Owen MJ, Hardy J, Goate A. Full genome screen for Alzheimer disease: Stage II analysis. Am J Med Genet. 2002 Mar 8; 114:235-244 [PubMed]
  19. Wessman M, Kallela M, Kaunisto MA, Marttila P, Sobel E, Hartiala J, Oswell G, Leal SM, Papp JC, Hamalainen E, Broas P, Joslyn G, Hovatta I, Hiekkalinna T, Kaprio J, Ott J, Cantor RM, Zwart JA, Ilmavirta M, Havanka H, Farkkila M, Peltonen L, Palotie A.et al. A Susceptibility Locus for Migraine with Aura, on Chromosome 4q24. Am J Hum Genet. 2002 Mar;70(3):652-62. [PubMed]
  20. Gretarsdottir S, Sveinbjornsdottir S, Jonsson HH, Jakobsson F, Einarsdottir E, Agnarsson U, Shkolny D, Einarsson G, Gudjonsdottir HM, Valdimarsson EM, Einarsson OB, Thorgeirsson G, Hadzic R, Jonsdottir S, Reynisdottir ST, Bjarnadottir SM, Gudmundsdottir T, Gudlaugsdottir GJ, Gill R, Lindpaintner K, Sainz J, Hannesson HH, Sigurdsson GT, Frigge ML, Kong A, Gudnason V, Stefansson K, Gulcher JR. Localization of a Susceptibility Gene for Common Forms of Stroke to 5q12. Am J Hum Genet 2002 Mar;70(3):593-603  [PubMed]
  21. Tiret L, Poirier O, Nicaud V, Barbaux S, Herrmann SM, Perret C, Raoux S, Francomme C, Lebard G, Tregouet D, Cambien F. Heterogeneity of linkage disequilibrium in human genes has implications for association studies of common diseases. Hum Mol Genet. 2002 Feb 15;11(4):419-429. [PubMed]
  22. Broeckel U, Hengstenberg C, Mayer B, Holmer S, Martin LJ, Comuzzie AG, Blangero J, Nurnberg P, Reis A, Riegger GA, Jacob HJ, Schunkert H. A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet. 2002 Feb;30(2):210-4 [PubMed]
  23. Busfield F, Duffy DL, Kesting JB, Walker SM, Lovelock P, Good D, Tate H, Watego D, Marczak M, Hayman N, Shaw JT. A Genomewide Search for Type 2 Diabetes-Susceptibility Genes in Indigenous Australians. Am J Hum Genet 2002 Feb;70(2):349-357 [PubMed]
  24. The SLI Consortium. A Genomewide Scan Identifies Two Novel Loci Involved in Specific Language Impairment. Am J Hum Genet. 2002 Feb; 70[epub ahead of print][PubMed]
  25. Lindgren CM, Mahtani MM, Widen E, McCarthy MI, Daly MJ, Kirby A, Reeve MP, Kruglyak L, Parker A, Meyer J, Almgren P, Lehto M, Kanninen T, Tuomi T, Groop LC, Lander ES. Genomewide Search for Type 2 Diabetes Mellitus Susceptibility Loci in Finnish Families: The Botnia Study. Am J Hum Genet. 2002 Feb;70(2):509-16. [PubMed]
  26. Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing C, Gillanders E, Hu P, Bujnovszky P, Makalowska I, Baffoe-Bonnie A, Faith D, Smith J, Stephan D, Wiley K, Brownstein M, Gildea D, Kelly B, Jenkins R, Hostetter G, Matikainen M, Schleutker J, Klinger K, Connors T, Xiang Y, Wang Z, De Marzo A, Papadopoulos N, Kallioniemi OP, Burk R, Meyers D, Gronberg H, Meltzer P, Silverman R, Bailey-Wilson J, Walsh P, Isaacs W, Trent J. Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet. 2002 Feb;30(2):181-184. [PubMed]
  27. Thompson D, Szabo CI, Mangion J, Oldenburg RA, Odefrey F, Seal S, Barfoot R, Kroeze-Jansema K, Teare D, Rahman N, Renard H, KConFab Consortium, Mann G, Hopper JL, Buys SS, Andrulis IL, Senie R, Daly MB, West D, Ostrander EA, Offit K, Peretz T, Osorio A, Benitez J, Nathanson KL, Sinilnikova OM, Olah E, Bignon YJ, Ruiz P, Badzioch MD, Vasen HF, Futreal AP, Phelan CM, Narod SA, Lynch HT, Ponder BA, Eeles RA, Meijers-Heijboer H, Stoppa-Lyonnet D, Couch FJ, Eccles DM, Evans DG, Chang-Claude J, Lenoir G, Weber BL, Devilee P, Easton DF, Goldgar DE, Stratton MR. Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast  Cancer Linkage Consortium.  Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):827-831. [PubMed][pdf]
  28. Arya R, Duggirala R, Almasy L, Rainwater DL, Mahaney MC, Cole S, Dyer TD, Williams K, Leach RJ, Hixson JE, MacCluer JW, O'Connell P, Stern MP, Blangero J. Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans. Nat Genet. 2002 Jan; 30:102-105 [PubMed]
  29. Fisher SE, Francks C, Marlow AJ, MacPhie IL, Newbury DF, Cardon LR, Ishikawa-Brush Y, Richardson AJ, Talcott JB, Gayan J, Olson RK, Pennington BF, Smith SD, DeFries JC, Stein JF, Monaco AP. Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia. Nat Genet. 2002 Jan; 30:86-91 [PubMed][web supplement]
  30. Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, Lusis AJ. Positional cloning of the combined hyperlipidemia gene Hyplip1. Nat Genet. 2002 Jan; 30:110-116 [PubMed]
Sibpair
  1. Boomsma D, Busjahn A, Peltonen L. Classical twin studies and beyond. Nat Rev Genet. 2002 Nov;3(11):872-82. [PubMed]
  2. Furushima K, Shimo-Onoda K, Maeda S, Nobukuni T, Ikari K, Koga H, Komiya S, Nakajima T, Harata S, Inoue I. Large-scale screening for candidate genes of ossification of the posterior longitudinal ligament of the spine. J Bone Miner Res. 2002 Jan;17(1):128-37. [PubMed]
Linkage disequilibrium
  1. Dawson E, Abecasis GR, Bumpstead S, Chen Y, Hunt S, Beare DM, Pabial J, Dibling T, Tinsley E, Kirby S, Carter D, Papaspyridonos M, Livingstone S, Ganske R, Lohmussaar E, Zernant J, Tonisson N, Remm M, Magi R, Puurand T, Vilo J, Kurg A, Rice K, Deloukas P, Mott R, Metspalu A, Bentley DR, Cardon LR, Dunham I. A first-generation linkage disequilibrium map of human chromosome 22. Nature. 2002 Aug 1;418(6897):544-8. [PubMed][web supplement]
  2. Katoh T, Mano S, Ikuta T, Munkhbat B, Tounai K, Ando H, Munkhtuvshin N, Imanishi T, Inoko H, Tamiya G. Genetic Isolates in East Asia: A Study of Linkage Disequilibrium in the X Chromosome. Am J Hum Genet 2002 Aug;71(2):395-400 [PubMed]
  3. Kirk BW, Feinsod M, Favis R, Kliman RM, Barany F. Single nucleotide polymorphism seeking long term association with complex disease. Nucleic Acids Res. 2002 Aug 1;30(15):3295-311. [PubMed]
  4. Schulze TG, Chen YS, Akula N, Hennessy K, Badner JA, McInnis MG, DePaulo JR, Schumacher J, Cichon S, Propping P, Maier W, Rietschel M, Nothen MM, McMahon FJ. Can long-range microsatellite data be used to predict short-range linkage disequilibrium? Hum Mol Genet. 2002 Jun 1;11(12):1363-1372. [PubMed]
  5. Sawcer S, Maranian M, Setakis E, Curwen V, Akesson E, Hensiek A, Coraddu F, Roxburgh R, Sawcer D, Gray J, Deans J, Goodfellow PN, Walker N, Clayton D, Compston A. A whole genome screen for linkage disequilibrium in multiple sclerosis confirms disease associations with regions previously linked to susceptibility. Brain. 2002 Jun;125(Pt 6):1337-1347. [PubMed]
  6. Stumpf MP. Haplotype diversity and the block structure of linkage disequilibrium. Trends Genet. 2002 Jun; 18: 226-228 [PubMed]
  7. Hall D, Wijsman EM, Roos JL, Gogos JA, Karayiorgou M. Extended intermarker linkage disequilibrium in the afrikaners. Genome Res. 2002 Jun;12(6):956-61. [PubMed]
  8. Reeve JP, Rannala B. DMLE+: Bayesian linkage disequilibrium gene mapping. Bioinformatics. 2002 Jun;18(6):894-5. [PubMed]
  9. Ardlie KG, Kruglyak L, Seielstad M. Patterns of linkage disequilibrium in the human genome. Nat Rev Genet. 2002 Apr;3(4):299-309.[PubMed]
  10. Trikka D, Fang Z, Renwick A, Jones SH, Chakraborty R, Kimmel M, Nelson DL. Complex SNP-Based Haplotypes in Three Human Helicases: Implications for Cancer Association Studies. Genome Res. 2002 Apr;12(4):627-39. [PubMed][web supplement]
  11. Shaw SH, Hutchison D, Saiz R, Abel K, Delisi LE, Schork NJ, Sherrington R. Evaluation of linkage disequilibrium between chromosome 22q11 single nucleotide polymorphisms in a large outbred population. Am J Med Genet. 2002 Mar 8;114(2):205-13.[PubMed]
  12. Hewett D, Samuelsson L, Polding J, Enlund F, Smart D, Cantone K, See CG, Chadha S, Inerot A, Enerback C, Montgomery D, Christodolou C, Robinson P, Matthews P, Plumpton M, Wahlstrom J, Swanbeck G, Martinsson T, Roses A, Riley J, Purvis I. Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map. Genomics. 2002 Mar;79(3):305-14. [PubMed]
  13. Nordborg M, Borevitz JO, Bergelson J, Berry CC, Chory J, Hagenblad J, Kreitman M, Maloof JN, Noyes T, Oefner PJ, Stahl EA, Weigel D. The extent of linkage disequilibrium in Arabidopsis thaliana. Nat Genet. 2002 Feb;30(2):190-3. [PubMed]
  14. Nordborg M, Tavare' S. Linkage disequilibrium: what history has to tell us. Trends Genet. 2002 Feb; 18:83-90 [PubMed]
  15. Weiss KM, Clark AG. Linkage disequilibrium and the mapping of complex human traits. Trends Genet. 2002 Jan; 18:19-24 [PubMed]
Quantitative Trait Loci (QTL)
  1. Moore AJ, Kukuk PF. Quantitative genetic analysis of natural populations. Nat Rev Genet. 2002 Dec; 3:971. [PubMed]
  2. Marshall KE, Godden EL, Yang F, Burgers S, Buck KJ, Sikela JM. In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases. Genome Biol. 2002 Dec; 3(12):RESEARCH0078. [PubMed][pdf]
  3. Lange C, DeMeo DL, Laird NM. Power and design considerations for a general class of family-based association tests: quantitative traits. Am J Hum Genet. 2002 Dec;71(6):1330-41. [PubMed]
  4. Darvasi A, Pisante-Shalom A. Complexities in the genetic dissection of quantitative trait loci. Trends Genet. 2002 Oct; 18:489-491 [PubMed]
  5. Bachmanov AA, Reed DR, Li X, Li S, Beauchamp GK, Tordoff MG. Voluntary Ethanol Consumption by Mice: Genome-Wide Analysis of Quantitative Trait Loci and Their Interactions in a C57BL/6ByJ x 129P3/J F(2) Intercross. Genome Res. 2002 Aug;12(8):1257-68. [PubMed][web supplement]
  6. Feingold E. Regression-Based Quantitative-Trait–Locus Mapping in the 21st Century. Am. J. Hum. Genet. 2002 Jul; 71:217-222. [PubMed]
  7. Phillips TJ, Belknap JK. Complex-trait genetics: emergence of multivariate strategies. Nat Rev Neurosci. 2002 Jun;3(6):478-85. [PubMed]
  8. Sham PC, Purcell S, Cherny SS, Abecasis GR. Powerful Regression-Based Quantitative-Trait Linkage Analysis of General Pedigrees. Am J Hum Genet. 2002 Aug;71(2):238-53. [PubMed]
  9. Etzel CJ, Guerra R. Meta-analysis of Genetic-Linkage Analysis of Quantitative-Trait Loci. Am J Hum Genet. 2002 Jul;71(1):56-65. [PubMed]
  10. Korstanje R, Paigen B. From QTL to gene: the harvest begins. Nat Genet. 2002 Jul;31(3):235-6. [PubMed]
  11. Steinmetz LM, Sinha H, Richards DR, Spiegelman JI, Oefner PJ, McCusker JH, Davis RW. Dissecting the architecture of a quantitative trait locus in yeast. Nature. 2002 Apr 21;416(6878):326-30. [PubMed][web supplement]
  12. Abney M, Ober C, McPeek MS. Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the hutterites. Am J Hum Genet. 2002 Apr;70(4):920-34. [PubMed]
  13. Fernandez-Teruel A, Escorihuela RM, Gray JA, Aguilar R, Gil L, Gimenez-Llort L, Tobena A, Bhomra A, Nicod A, Mott R, Driscoll P, Dawson GR, Flint J. A quantitative trait locus influencing anxiety in the laboratory rat. Genome Res. 2002 Apr;12(4):618-26. [PubMed]
  14. Allison DB, Fernandez JR, Heo M, Zhu S, Etzel C, Beasley TM, Amos CI. Bias in Estimates of Quantitative-Trait Locus Effect in Genome Scans: Demonstration of the Phenomenon and a Method-of-Moments Procedure for Reducing Bias. Am J Hum Genet 2002 Mar;70(3):575-85 [PubMed]
  15. Grisart B, Coppieters W, Farnir F, Karim L, Ford C, Berzi P, Cambisano N, Mni M, Reid S, Simon P, Spelman R, Georges M, Snell R. Positional Candidate Cloning of a QTL in Dairy Cattle: Identification of a Missense Mutation in the Bovine DGAT1 Gene with Major Effect on Milk Yield and Composition. Genome Res. 2002 Feb;12(2):222-31. [PubMed]
  16. Wu R, Ma CX, Casella G. Joint linkage and linkage disequilibrium mapping of quantitative trait Loci in natural populations. Genetics. 2002 Feb;160(2):779-92. [PubMed]
  17. Doerge RW. MAPPING AND ANALYSIS OF QUANTITATIVE TRAIT LOCI IN EXPERIMENTAL POPULATIONS. Nat Rev Genet. 2002 Jan; 3:43-52 [PubMed]
  18. Barton NH, Keightley PD. UNDERSTANDING QUANTITATIVE GENETIC VARIATION. Nat Rev Genet. 2002 Jan;3(1):11-21. [PubMed]
  19. Jacob HJ, Kwitek AE. Multifactorial genetics RAT GENETICS: ATTACHING PHYSIOLOGY AND PHARMACOLOGY TO THE GENOME. Nat Rev Genet. 2002 Jan;3(1):33-42. [PubMed]
  20. CORANDER J, SILLANPAA M. A unified approach to joint modeling of multiple quantitative and qualitative traits in gene mapping. J Theor. Biol. 2002; 218:435-446. [PubMed]


Theoretical development

  1. Zhang K, Calabrese P, Nordborg M, Sun F. Haplotype Block Structure and Its Applications to Association Studies: Power and Study Designs. Am J Hum Genet. 2002 Dec;71(6):1386-94. [PubMed]
  2. Lange C, DeMeo DL, Laird NM. Power and Design Considerations for a General Class of Family-Based Association Tests: Quantitative Traits. Am J Hum Genet. 2002 Dec;71(6):1330-41. [PubMed]
  3. Schliekelman P, Slatkin M. Multiplex Relative Risk and Estimation of the Number of Loci Underlying an Inherited Disease. Am J Hum Genet. 2002 Dec;71(6):1369-85. [PubMed]
  4. Terwilliger JD, Haghighi F, Hiekkalinna TS, Goring HH. A bias-ed assessment of the use of SNPs in human complex traits. Curr Opin Genet Dev 2002 Dec; 12:726-734. [PubMed]
  5. Zhang K, Calabrese P, Nordborg M, Sun F. Haplotype block structure and its applications to association studies: power and study designs. Am J Hum Genet. 2002 Dec;71(6):1386-94. [PubMed]
  6. Lange C, DeMeo DL, Laird NM. Power and design considerations for a general class of family-based association tests: quantitative traits. Am J Hum Genet. 2002 Dec;71(6):1330-41. [PubMed]
  7. Wiltshire S, Cardon LR, McCarthy MI. Evaluating the Results of Genomewide Linkage Scans of Complex Traits by Locus Counting. Am J Hum Genet 2002 Nov;71(5):1175-82 [PubMed]
  8. Sham PC, Purcell S, Cherny SS, Abecasis GR. Powerful Regression-Based Quantitative-Trait Linkage Analysis of General Pedigrees. Am J Hum Genet. 2002 Aug;71(2):238-53. [PubMed]
  9. Schulze TG, Chen YS, Akula N, Hennessy K, Badner JA, McInnis MG, DePaulo JR, Schumacher J, Cichon S, Propping P, Maier W, Rietschel M, Nothen MM, McMahon FJ. Can long-range microsatellite data be used to predict short-range linkage disequilibrium? Hum Mol Genet. 2002 Jun 1;11(12):1363-1372. [PubMed]
  10. Qian D, Beckmann L. Minimum-Recombinant Haplotyping in Pedigrees. Am J Hum Genet. 2002 Jun;70(6):1434-1445. [PubMed]
  11. Schork NJ. Power Calculations for Genetic Association Studies Using Estimated Probability Distributions. Am J Hum Genet. 2002 Jun;70(6):1480-9.[PubMed]
  12. Sillanpaa MJ, Corander J. Model choice in gene mapping: what and why. Trends Genet. 2002 Jun; 18: 301-307 [PubMed]
  13. Xiong M, Zhao J, Boerwinkle E. Generalized T2 Test for Genome Association Studies. Am J Hum Genet. 2002 May;70(5):1257-68. [PubMed]
  14. Allison DB, Fernandez JR, Heo M, Zhu S, Etzel C, Beasley TM, Amos CI. Bias in Estimates of Quantitative-Trait Locus Effect in Genome Scans: Demonstration of the Phenomenon and a Method-of-Moments Procedure for Reducing Bias. Am J Hum Genet 2002 Mar;70(3):575-85[PubMed]
  15. Dahlman I, Eaves IA, Kosoy R, Morrison VA, Heward J, Gough SC, Allahabadia A, Franklyn JA, Tuomilehto J, Tuomilehto-Wolf E, Cucca F, Guja C, Ionescu-Tirgoviste C, Stevens H, Carr P, Nutland S, McKinney P, Shield JP, Wang W, Cordell HJ, Walker N, Todd JA, Concannon P. Parameters for reliable results in genetic association studies in common disease. Nat Genet. 2002 Feb;30(2):149-50. [PubMed]
  16. Niu T, Qin ZS, Xu X, Liu JS. Bayesian Haplotype Inference for Multiple Linked Single-Nucleotide Polymorphisms. Am J Hum Genet. 2002 Jan;70(1):157-169.[PubMed]
Software
  1. Reeve JP, Rannala B. DMLE+: Bayesian linkage disequilibrium gene mapping. Bioinformatics. 2002 Jun;18(6):894-5. [PubMed]
  2. Zhang K, Deng M, Chen T, Waterman MS, Sun F. A dynamic programming algorithm for haplotype block partitioning. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7335-9. [PubMed][pdf]
  3. Seaton G, Haley CS, Knott SA, Kearsey M, Visscher PM. QTL Express: mapping quantitative trait loci in simple and complex pedigrees. Bioinformatics. 2002 Feb;18(2):339-340. [PubMed]
  4. Voorrips RE. MapChart: Software for the Graphical Presentation of Linkage Maps and QTLs. J Hered. 2002 Jan-Feb;93(1):77-8. [PubMed]
  5. Abecasis GR, Cherny SS, Cookson WO, Cardon LR. Merlin—rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet. 2002 Jan;30:97-101 [PubMed]
  6. Nicolae DL, Cox NJ. MERLIN…and the Geneticist’s Stone? Nat Genet. 2002 Jan; 30:3-4 [PubMed]
Database
 
 

Genetic map development

  1. Halapi E, Hakonarson H. Advances in the development of genetic markers for the diagnosis of disease and drug response. Expert Rev Mol Diagn. 2002 Sep;2(5):411-21. [PubMed]
  2. Conti C, Bensimon A. A Combinatorial Approach for Fast, High-Resolution Mapping. Genomics. 2002 Aug 1; 80: 135-137. [PubMed]
  3. Thomas JW, Prasad AB, Summers TJ, Lee-Lin SQ, Maduro VV, Idol JR, Ryan JF, Thomas PJ, McDowell JC, Green ED. Parallel construction of orthologous sequence-ready clone contig maps in multiple species. Genome Res. 2002 Aug;12(8):1277-85. [PubMed]
  4. Weber JL. The Iceland map. Nat Genet. 2002 Jul;31(3):225-6. [PubMed]
  5. Kong A, Gudbjartsson DF, Sainz J, Jonsdottir GM, Gudjonsson SA, Richardsson B, Sigurdardottir S, Barnard J, Hallbeck B, Masson G, Shlien A, Palsson ST, Frigge ML, Thorgeirsson TE, Gulcher JR, Stefansson K. A high-resolution recombination map of the human genome. Nat Genet. 2002 Jul;31(3):241-7. [PubMed][web supplement]
  6. High-resolution genetic map of the human genome (deCODE). Pharmacogenomics. 2002 Jul;3(4):440. [PubMed]
  7. Matise TC, Porter CJ, Buyske S, Cuttichia AJ, Sulman EP, White PS. Systematic Evaluation of Map Quality: Human Chromosome 22. Am J Hum Genet. 2002 Jun;70(6):1398-410. [PubMed]
  8. Weikard R, Kuhn C, Goldammer T, Laurent P, Womack JE, Schwerin M. Targeted construction of a high-resolution, integrated, comprehensive, and comparative map for a region specific to bovine chromosome 6 based on radiation hybrid mapping. Genomics. 2002 Jun;79(6):768-76. [PubMed]
  9. Goldammer T, Kata SR, Brunner RM, Dorroch U, Sanftleben H, Schwerin M, Womack JE. A comparative radiation hybrid map of bovine chromosome 18 and homologous chromosomes in human and mice. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2106-11. [PubMed][pdf][web supplement]
  10. Thoquet P, Gherardi M, Journet EP, Kereszt A, Ane JM, Prosperi JM, Huguet T. The molecular genetic linkage map of the model legume Medicago truncatula: an essential tool for comparative legume genomics and the isolation of agronomically important genes. BMC Plant Biol. 2002;2(1):1. [PubMed][pdf]
last updated: 5 Feb 2003
home