My complex disease trait mapping, genome mapping, linkage analysis journal watch - year 2000 [ this week | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 ]

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  1. Horvath S, Baur MP. Future directions of research in statistical genetics. Stat Med. 2000 Dec 30;19(24):3337-3343. [PubMed]
  2. Zavattari P, Deidda E, Whalen M, Lampis R, Mulargia A, Loddo M, Eaves I, Mastio G, Todd JA, Cucca F. Major factors influencing linkage disequilibrium by analysis of different chromosome regions in distinct populations: demography, chromosome recombination frequency and selection. Hum Mol Genet. 2000 Dec 12;9(20):2947-2957. [PubMed]
  3. Peltonen l, Palotie A, Lange K. Use of population isolates for mapping complex traits. Nature Reviews Genetics 2000 Dec; 1:182-190 [link to journal]
  4. Vadasz C. Analysis of complex traits: mutagenesis versus QTLs. Nat Genet. 2000 Dec;26(4):395. [PubMed]
  5. Gulcher J, Helgason A, Stefansson K. Genetic homogeneity of Icelanders. Nat Genet. 2000 Dec;26(4):395. [PubMed]
  6. Kaplan JC, Junien C.  Genomics and medicine: an anticipation. From Boolean Mendelian genetics to multifactorial molecular medicine.  C R Acad Sci III. 2000 Dec;323(12):1167-74. [PubMed]
  7. Bourgain C, Genin E, Holopainen P, Mustalahti K, Maki M, Partanen J, Clerget-Darpoux F. Use of Closely Related Affected Individuals for the Genetic Study of Complex Diseases in Founder Populations. Am J Hum Genet. 2000 Nov 30 [PubMed]
  8. McPeek MS. From mouse to human: Fine mapping of quantitative trait loci in a model organism. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12389-12390. [PubMed]
  9. Mott R, Talbot CJ, Turri MG, Collins AC, Flint J. A method for fine mapping quantitative trait loci in outbred animal stocks. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12649-12654. [PubMed]
  10. Weatherall DJ. Single gene disorders or complex traits: lessons from the thalassaemias and other monogenic diseases. BMJ. 2000 Nov 4;321(7269):1117-1120. [PubMed]
  11. Lee JK, Thomas DC. Performance of Markov Chain-Monte Carlo Approaches for Mapping Genes in Oligogenic Models with an Unknown Number of Loci. Am J Hum Genet. 2000 Nov;67(5):1232-1250. [PubMed]
  12. Watanabe RM, Ghosh S, Langefeld CD, Valle TT, Hauser ER, Magnuson VL, Mohlke KL, Silander K, Ally DS, Chines P, Blaschak-Harvan J, Douglas JA, Duren WL, Epstein MP, Fingerlin TE, Kaleta HS, Lange EM, Li C, McEachin RC, Stringham HM, Trager E, White PP, Balow Jr J, Birznieks G, Chang J, Eldridge W, Erdos MR, Karanjawala ZE, Knapp JI, Kudelko K, Martin C, Morales-Mena A, Musick A, Musick T, Pfahl C, Porter R, Rayman JB, Rha D, Segal L, Shapiro S, Sharaf R, Shurtleff B, So A, Tannenbaum J, Te C, Tovar J, Unni A, Welch C, Whiten R, Witt A, Kohtamaki K, Ehnholm C, Eriksson J, Toivanen L, Vidgren G, Nylund SJ, Tuomilehto-Wolf E, Ross EH, Demirchyan E, Hagopian WA, Buchanan TA, Tuomilehto J, Bergman RN, Collins FS, Boehnke M. The Finland-United States Investigation of Non-Insulin-Dependent Diabetes Mellitus Genetics (FUSION)  Study. II. An Autosomal Genome Scan for Diabetes-Related Quantitative-Trait Loci.  Am J Hum Genet. 2000 Nov;67(5):1186-1200. [PubMed]
  13. Ghosh S, Watanabe RM, Valle TT, Hauser ER, Magnuson VL, Langefeld CD, Ally DS, Mohlke KL, Silander K, Kohtamaki K, Chines P, Balow Jr J, Birznieks G, Chang J, Eldridge W, Erdos MR, Karanjawala ZE, Knapp JI, Kudelko K, Martin C, Morales-Mena A, Musick A, Musick T, Pfahl C, Porter R, Rayman JB, Rha D, Segal L, Shapiro S, Sharaf R, Shurtleff B, So A, Tannenbaum J, Te C, Tovar J, Unni A, Welch C, Whiten R, Witt A, Blaschak-Harvan J, Douglas JA, Duren WL, Epstein MP, Fingerlin TE, Kaleta HS, Lange EM, Li C, McEachin RC, Stringham HM, Trager E, White PP, Eriksson J, Toivanen L, Vidgren G, Nylund SJ, Tuomilehto-Wolf E, Ross EH, Demirchyan E, Hagopian WA, BuchananTA, Tuomilehto J, Bergman RN, Collins FS, Boehnke M. The Finland-United States Investigation of Non-Insulin-Dependent Diabetes Mellitus Genetics (FUSION) Study. I. An Autosomal Genome Scan for Genes That Predispose to Type 2 Diabetes. Am J Hum Genet. 2000 Nov;67(5):1174-1185. [PubMed]
  14. Davidson S. Research suggests importance of haplotypes over SNPs. Nat Biotechnol. 2000 Nov;18(11):1134-1135. [PubMed]
  15. Jorde LB. Linkage Disequilibrium and the Search for Complex Disease Genes. Genome Res. 2000 Oct;10(10):1435-1444. [PubMed]
  16. Weiss KM, Terwilliger JD.How many diseases does it take to map a gene with SNPs? Nat Genet. 2000 Oct;26(2):151-157. No abstract available. [PubMed]
  17. Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE,del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct;26(2):163-175. [PubMed]
  18. Irizarry K, Kustanovich V, Li C, Brown N, Nelson S, Wong W, Lee CJ. Genome-wide analysis of single-nucleotide polymorphisms in human expressed sequences. Nat Genet. 2000 Oct;26(2):233-236. [PubMed]
  19. Gray IC, Campbell DA, Spurr NK. Single nucleotide polymorphisms as tools in human genetics. Hum Mol Genet. 2000 Oct 12;9(16):2403-2408. [PubMed]
  20. Miano MG, Jacobson SG, Carothers A, Hanson I, Teague P, Lovell J, Cideciyan AV, Haider N, Stone EM, Sheffield VC, Wright AF. Pitfalls in Homozygosity Mapping. Am J Hum Genet. 2000 Sep 27 [epub ahead of print] [PubMed]
  21. Zhao H, Zhang S, Merikangas KR, Trixler M, Wildenauer DB, Sun F, Kidd KK.Transmission/Disequilibrium Tests Using Multiple Tightly Linked Markers. Am J Hum Genet. 2000 Aug 31 [epub ahead of print] [PubMed]
  22. Nadeau JH, Frankel WN.The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs. Nat Genet. 2000 Aug;25(4):381-4. [PubMed]
  23. Arnason E, Sigurgislason H, Benedikz E. Genetic homogeneity of Icelanders: fact or fiction? Nat Genet. 2000 Aug;25(4):373-4. No abstract available. [PubMed]
  24. Nyholt DR. All LODs are not created equal. Am J Hum Genet. 2000 Aug;67(2):282-8.
  25. Frary A, Nesbitt TC, Grandillo S, Knaap E, Cong B, Liu J, Meller J, Elber R, Alpert KB, Tanksley SD. fw2.2: a quantitative trait locus key to the evolution of tomato fruit size. Science. 2000 Jul 7;289(5476):85-8. [PubMed]
  26. Woolley AT, Guillemette C, Li Cheung C, Housman DE, Lieber CM. Direct haplotyping of kilobase-size DNA using carbon nanotube probes. Nat Biotechnol. 2000 Jul;18(7):760-3. [PubMed]
  27. Taton TA, Mirkin CA. Haplotyping by force.  Nat Biotechnol. 2000 Jul;18(7):713. [PubMed]
  28. Risch NJ. Searching for genetic determinants in the new millennium. Nature. 2000 Jun 15;405(6788):847-56. Review. [PubMed]

last updated: 21 Oct 2001
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