Welcome

 

Prof CHAN Wood Yee 陳活彜
B.Sc., M.Phil., Ph.D., C.Biol., M.I.Biol.
Email:  wy-chan@cuhk.edu.hk
Tel:  (852)3943 6895
Fax: (852)2603 5031

 

 

 

 

 

RECENT PUBLICATIONS

We have been publishing widely in internationally refereed journals which include Gastroenterology, Cell transplantation, Brain Research Reviews, Development, Developmental Brain Research, Neuroscience, Anatomical Record, Anatomy and Embryology, Journal of Anatomy, Journal of Experimental Zoology, Oncogene, etc. In the recent 5 years, we have already published over 30 papers.  One or two selected paper from each year is listed below as examples:

- Wang X, Chan AKK, Sham MH, Burns AJ and Chan WY (2011) Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo.  Gastroenterology 141(3): 992-1002.

- Qu ZQ, Zhou Y, Zeng YS, Lin YK, Li Y, Zhong ZQ, Chan WY (2012) Protective effects of a Rhodiola crenulata extract and salidroside on hippocampal neurogenesis against streptozotocin-induced neural injury in the rat. PLoS One 7(1):e29641.

- Zeng X, Zeng Y, Ma Y, Lu L, Du B, Zhang W, Li Y and Chan WY (2011) Bone marrow mesenchymal stem cells in a three dimensional gelatine sponge scaffold attenuate inflammation, promote angiogenesis and reduce cavity formation in experimental spinal cord injury.  Cell Transplantation (in press)

- Chan WY, Ng TB, Lam JSY, Wong JH, Chu KT, Ngai PHK, Lam SK and Wang HX (2010) The mushroom ribosome-inactivating protein lyophyllin exerts deleterious effects on mouse embryonic development in vitro.  Applied Microbiology and Biotechnology  85: 985-994.

- Chan WY, Xia CL, Yew DT, Zhao H and Mok SC (2009) Expression of Dab2, a tumor suppressor, in the human fetal hippocampus and neocortex.  Neuroembryology and Aging 5: 182-190.

- Cheung KK, Mok SC, Rezaie P and Chan WY (2008) Dynamic expression of Dab2 in the mouse embryonic central nervous system. BMC Developmental Biology 8: 76.

- Chan WY, Kohsaka S and Rezaie P (2007) The origin and cell lineage of microglia – New concepts.  Brain Research Reviews 53: 344-354.

- Li KKH, Sung RYT, Huang WZ, Yang M, Pong NH, Lee SM, Chan WY, Zhao H, To MY, Fok TF, Li CK, Wong YO and Ng HK (2006) Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin.  Circulation 113: 2211-2220.

- Cheung KK, Chan WY and Burnstock G (2005) Expression of P2X purinoceptors during rat brain development and their Inhibitory role on motor axon outgrowth in neural tube explant cultures. Neuroscience 133: 937-945.

- Chan WY, Cheung CS, Yung KM and Copp AJ (2004) Cardiac neural crest of the mouse embryo: axial level of origin, migratory pathway and cell autonomy of the splotch (Sp2H) mutant. Development 131: 3367-3379.

- Chan WY, Lorke DE, Tiu SC and Yew DT (2002) Proliferation and apoptosis in the developing human neocortex. Anatomical Record 267: 261-276.

- Fan M, Mi R, Yew DT and Chan WY (2001) Analysis of gene expression following sciatic nerve crush and spinal cord hemisection in the mouse by microarray expression profiling. Cellular and Molecular Neurobiology 21: 497-508.

- Chan WY, Cheung KK, Schorge JO, Huang LW, Welch WR, Bell DA, Berkowitz RS and Mok SC (2000) Relationship of bcl-2 and p53 protein expression, apoptosis and p53 mutation in human epithelial ovarian cancers. American Journal of Pathology 156: 409-417.

- Yew DT and Chan WY (1999) Early appearance of acetylcholinergic, serotoninergic and peptidergic neurons and fibers in the developing human central nervous system. Microscopy Research and Technique 45: 389-400.

- Mok SC, Chan WY, Cheung KK, Wong KK, Lau CC, Baldinin A, Colitti CV, Rock C and Berkowitz RS (1998) Doc-2, a novel putative tumor suppressor gene in human epithelial ovarian cancer. Oncogene 16: 2381-2387.