My profile


(*selected information is listed here, a full CV is available upon request)
Personal particulars
Present appointment
Previous appointments
Education
Grant
Academic achievements and awards
Professional service - teaching
Professional service - lectures
Professional service - reviewing
Professional service - functional genomics web site creation
Specialist training
Attendence of international conferences
Computer skill
Language proficiency
Publications
References

PERSONAL PARTICULARS

Name: Leung, Yuk Fai (梁旭輝)
Telephone no.: (office)    617-495-2599
                           (fax)   617-496-3321
Address: Department of Molecular and Cellular Biology, Harvard University, BL 2079, 16 Divinity Avenue, Cambridge, MA 02138, USA
email: yfleung@genomicshome.com
URL: http://genomicshome.comhttp://ihome.cuhk.edu.hk/~b400559
 

PRESENT APPOINTMENT

November 2002 - now Croucher Foundation Postdoctoral Fellow
Bauer Center for Genomics Research & Department of Molecular and Cellular Biology
Harvard University
Research interest: Genome scale pathway reconstruction by microarray expression profiling: from simple yeast to complex zebrafish model. 

PREVIOUS APPOINTMENTS

October 1998 - October 2002 Research Assistant 
Department of Ophthalmology and Visual Sciences
Chinese University of Hong Kong 
-conducted genetic and microarray researches on eye diseases including glaucoma, age related macular degeneration, myopia, cataract and aniridia
-established Molecular Genetics and Genomic Laboratory for microarray analysis, automated sequencing, whole genome mapping, linkage analysis, mutation study.

EDUCATION

1999-2002  PhD in Ophthalmology and Visual Science
Department of Opthalmology and Visual Science 
Chinese University of Hong Kong
Thesis title: Hereditary Primary Open Angle Glaucoma: From Molecular Genetics to Genomics
1996-1998 MPhil in Biochemistry 
Hong Kong University of Science and Technology
Thesis title: Baculovirus co-expression and purification of CDK5 and p35nck5a
1993-1996 Bsc in Biochemistry (First Class Honours)
Hong Kong University of Science and Technology

GRANT

2004   Croucher Foundation Research Allowance

ACADEMIC ACHIEVEMENTS AND AWARDS

2004
Listed in Marquis Who’s Who in Science and Engineering, 8th edition
2004
Student Scholarship
Neural Development and Genetics of Zebrafish
Marine Biological Laboratory
2002-2004 Croucher Foundation Postdoctoral Fellowship
2002
Action for Vision Young Researcher of the Year
2001 Action for Vision Green Researcher of the Year
September 1996-August 1998 Postgraduate Studentship
Hong Kong University of Science and Technology
Spring 1996 Dean's List
Hong Kong University of Science and Technology
Fall 1993 Parfums Christian Dior Skincare Scholarship in Biochemistry
Christian Dior Co. Ltd.

PROFESSIONAL SERVICE - TEACHING

15 July 2004
A Biologist’s Guide to Microarray Data Analysis with Bioconductor (invited)
CGR, Harvard University
Cambridge, MA, USA
15 June 2004
A Biologist’s Guide to Microarray Data Analysis with Bioconductor (invited)
CGR, Harvard University
Cambridge, MA, USA

PROFESSIONAL SERVICE - LECTURES

16 October 2003
“Fundamentals of microarray analysis” (invited)
Genome Research Centre
University of Hong Kong
Hong Kong, China
13 October 2003
“Microarray Mutation Analysis” (invited)
Clinical Genetics Service Center
Department of Health
Hong Kong, China
7 October 2003
 “Fundamentals of cDNA microarray analysis” (invited)
Prince of Wales Hospital
Chinese University of Hong Kong
Hong Kong, China
6 October 2003
“In vino veritas - acetic acid stress response of natural wine yeasts” (invited)
Department of Ophthalmology and Visual Sciences
Chinese University of Hong Kong
Hong Kong, China
2-5 October 2002 "Microarray Analysis of Glaucoma Genes - The dual role of dexamethasone on anti-inflammation and outflow resistance in trabecular meshwork " (Invited)
Joint European Research Meetings in Ophthalmology and Vision
European Association for Vision and Eye Research
Alicante, Spain
21-26 April 2002 "Microarray Analysis of Glaucoma Genes"
XXIXth International Congress of Ophthalmology
Sydney, Australia
5-8 March 2002 "Microarray Softwares Review" (Invited)
EMBnet DNA Microarrays course 2002
Swiss European Molecular Biology Network (EMBnet) Node
Swiss Institute of Bioinformatics
Lausanne, Switzerland
4 July 2001 "Eye diseases research - from genes to genome"
Division of Nephrology; Department of Medicine
McMaster University
Ontario, Canada
17 October 2000 "Molecular Genetics of Glaucoma" 
Shanghai Institute of Medical Genetics
Shanghai, China

PROFESSIONAL SERVICE - REVIEWING

External reviewer for the following research grant:

2002    Academic Research Fund, University Research Committee, National University of Singapore

Ad hoc reviewer for the book proposal from the following publisher:

2004     Wiley, New York

Ad hoc reviewer for the following journals:

2004    Bioinformatics, BMC Bioinformatics, IEEE Transactions on Image Processing, Molecular Biotechnology, Physiological Genomics
2003    Journal of VLSI Signal Processing - Special Issue on Genomic Signal Processing, Molecular Vision
2002    Briefings in Bioinformatics, IEEE Computer on bioinformatics software systems, Thrombosis Research

2001    Journal of Real Time Imaging - Special Issue on Imaging in Bioinformatics

Ad hoc reviewer for the following software:

2001    Database Referencing of Genes ONline (DRAGON), Wiley, New York
 

PROFESSIONAL SERVICE - FUNCTIONAL GENOMICS WEB SITE CREATION

13 June 2000 - now yfleung's functional genomics home
http://genomicshome.com; http://ihome.cuhk.edu.hk/~b400559
-a functional genomics portal focuses on genomics, microarray technologies, bioinformatics, proteomics and complex disease trait mapping. 
-provided a comprehensive archive of related journal publications 
-provided a comprehensive microarray software listing
-reviewed by Science Magazine 2001 Oct;294:483.

SPECIALIST TRAINING

15-28 August 2004
Neural Development & Genetics of Zebrafish
Marine Biological Laboratory
Woods Hole, MA, USA
28-29 June 2004
Bioconductor training Boston 2004
Channing Lab, Harvard University
Longwood Medical Area, Boston, MA, USA
2 June 2004
Promoter Analysis
Computational Biology Group, CGR, Harvard University
Cambridge, MA, USA
11 August 2003
Advanced Rosetta Training.
Computational Biology Group, CGR, Harvard University
Cambridge, MA, USA
28 July 2003
Introduction to Microarray Analysis and Rosetta Resolver.
Computational Biology Group, CGR, Harvard University
Cambridge, MA, USA
10 June 2003
A Field Guide to GenBank and NCBI Molecular Resources.
NCBI, Harvard University
Cambridge, MA, USA
29 May 2003
Introduction to EMBOSS.
Computational Biology Group, CGR, Harvard University
Cambridge, MA, USA
15 May 2003
Functional Discovery.
Computational Biology Group, CGR, Harvard University
Cambridge, MA, USA
2 May 2003
Biocomputing on the web.
Computational Biology Group, CGR, Harvard University
Cambridge, MA, USA
18-20 April 2002 Design and Analysis of DNA Microarray Studies
Rockefeller University
New York, USA
4-8 March 2002 DNA microarrays 2002
European Molecular Biology Network (Swiss node)
Swiss Institute of Bioinformatics
Switzerland
13-14 December 2000 Two Dimensional Electrophoresis & Image Analysis Workshop
Amersham Pharmacia Biotech Ltd.
Department of Anatomy, Faculty of Medicine,The University of Hong Kong, Hong Kong
12 December 2000 Laser Capture Microdissection (LCM) Workshop: LM200 - Introduction and application
Arcturus & Olympus
Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong
24-28 July 2000 Linkage Lab Course - An introduction to genotyping and linkage analysis
UK Human Genome Mapping Project Resource Centre
Genome Campus, Hinxton, Cambridge
10- 12 July 2000 Introductory Molecular Biology Computing
UK Human Genome Mapping Project Resource Centre
London

ATTENDANCE OF INTERNATIONAL CONFERENCES 

8-9 Januaray 2004
CSBi 2004 Symposium in Systems Biology "From Bioinformatics to Biofabrication"
MIT
Cambridge, MA, USA
9-10 January 2003
CSBi 2003 Annual Conference "From Bioinformatics to Biofabrication"
MIT
Cambridge, MA, USA
21-25 April 2002 XXIXth International Congress of Ophthalmology
Sydney, Australia
3-7 January 2002 Pacific Symposium on Biocomputing (PSB 2002)
Stanford University
Kauai, Hawaii, USA
21-22 June 2001 Fifth Annual Proteomics
Beyond Genome 2001
Cambridge Healthtech Institute
San Francisco, California, USA
19-20 June 2001  Third Annual In Silico Biology
Beyond Genome 2001
Cambridge Healthtech Institute
San Francisco, California, USA
17-19 June 2001 Tenth Annual Bioinformatics and Genome Research
Beyond Genome 2001
Cambridge Healthtech Institute
San Francisco, California, USA
11-13 June 2001  Eighth Annual HTT EXPO Advancing Drug Development 
Cambridge Healthtech Institute
Philadelphia, Pennsylvania, USA
4-5 June 2001 Microarrays and Microchips Japan
Cambridge Healthtech Institute
Tokyo, Japan
18-21 October 2000 The 3rd HUGO Pacific Meeting and the 4th Asia-Pacific Conference on Human Genetics - Disease-related Genomics
HUGO Pacific, Asia-Pacific Society of Human Genetics
Shanghai, China
16-20 July 2000 18th International Congress of Biochemistry and Molecular Biology: Beyond the Genome
International Union of Biochemistry and Molecular Biology, Federation of European Biochemical Societies and Biochemical Society.
Birmingham, UK
9-14 May 1999 The ARVO Annual Meeting
Association for Research in Vision and Ophthalmology
Fort Lauderdale, Florida, USA
November 1997 IMCB 10th Anniversary Symposium
Building Bridges to 21st Century Medicine: Genes, Signals and Diseases
Institute of Molecular and Cell Biology
Singapore

COMPUTER SKILL

Operating system  Windows, Linux/ UNIX, MacOS
Bioinformatics tools basic EMBOSS
Statistic programs R, Excel, SPSS
Microarray analysis Bionconductor, Statistics for Microarray Analysis (SMA) package, Rosetta Resolver, TIGR TM4, Cluster, Treeview, Expression Profiler, GenePix Pro, QuantArray, ImaGene, BRB ArrayTools
Computing language R, html, basic C, PERL and SQL
Database
basic Access and MySQL

LANGUAGE PROFICIENCY

Cantonese, English, Mandarin

PUBLICATIONS

(*you will be redirected to the publications' page)
 

REFERENCE

1. Professor John E. Dowling
    Department of Molecular and Cellular Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    E-mail : dowling@mcb.harvard.edu
    Phone : (6l7) 495-2245
    Fax : (617) 496-3321
    Web page:  http://www.mcb.harvard.edu/Faculty/Dowling.html

2. Doctor Duccio Cavalieri
    Bauer Center for Genomics Research, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
    E-mail : dcavalieri@cgr.harvard.edu
    Phone : (617) 384-7645
    Fax : (617) 495-2196
    Web page: http://cgr.harvard.edu/fellows_pages/cavalieri.html

3. Professor Dennis S.C. Lam
    Chairman, Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong
    Honorary Chief-of-Service, Hong Kong Eye Hospital
    E-mail : dennislam@cuhk.edu.hk
    Phone : (852) 2762 3157
    webpage: http://www.cuhk.edu.hk/medint/ovs/dl.htm

4. Professor Calvin C.P. Pang
    Director of Laboratory Research, Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong
    E-mail : cppang@cuhk.edu.hk
    Phone : (852) 2762 3129
    webpage: http://www.cuhk.edu.hk/medint/ovs/cp.htm

5. Professor Jerry H.C. WANG
    Former Department Head, Department of Biochemistry, Hong Kong University of Science and Technology
    E-mail : jerwang@ust.hk
    Phone: (852) 2358 8701
    webpage: http://www.ust.hk/~webbich/profiles/jhwang.html


last updated: 12 Sep 2004
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