My favorite complex disease trait mapping, genome mapping and linkage analysis books

 
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Biostatistical Genetics and Genetic Epidemiology
by Robert C. Elston (Editor), Jane M. Olson (Editor), Lyle Palmer (Editor)
Hardcover: 831 pages ; Dimensions (in inches): 2.01 x 9.96 x 7.68; Publisher: John Wiley & Sons; 1st edition (April 15, 2002); ISBN: 0471486310

Price: US$
415.00
Table of contents

Editorial Reviews
From Book News, Inc.
Provides an alphabetical reference source for articles relevant to the principles and practice of biostatistics in human genetics. Covers statistical aspects of most areas of genetic analysis, as well as many basic, widely used biostatistical methods. Articles, written by an international group of experts in genetic statistics, genetic epidemiology, and biostatistics, include both revised and updated articles drawn from John Wiley's Encyclopedia of Biostatistics and a number of other articles on such topics as admixture mapping, bioinformatics, family-based case- control studies, gene expression analysis, genetic heterogeneity, hierarchical models, kin- cohort studies, parental effects, pharmacogenetics, radiation hybrid mapping, and sequence analysis. Most articles assume a level of knowledge equivalent to that covered in introductory courses on statistical methods or mathematical statistics. Cross-referenced throughout.

Handbook of Statistical Genetics (2 Volume Set)
by D. J. Balding, Chris Cannings, Martin Bishop (Editor)
Hardcover: 1308 pages ; Dimensions (in inches): 3.28 x 10.02 x 7.68; Publisher: John Wiley & Sons; 2nd edition (September 5, 2003); ISBN: 0470848294  

Price: US$315.00

Amazon.com customers rating: 

Reviewer: A reader from St. Louis, MO, USA 
The book is a collection of chapters written by experts in their respective fields. It contains both basic  topics of genetics like chromosome maps and protein analysis as well as recent developments in evolutionary genetics like coalescence and phylogenetics. The topics on genetic epidemiology like linkage and association cover the main ideas, but the mathematical subtlities are not adequately explained in some of the cases. Since the target audience of this book are statistical geneticists, it would have been  more beneficial if more quantitative insights were given. The chapters by Bruce Weir, Nicholas Schork  and Ranajit Chakraborty provide some interesting practical applications of statistical genetics. With lots  of controversies going around, it is apt to include the chapter on the ethical issues regarding the use of statistics in genetics.


Genetic Dissection of Complex Traits (Advances in Genetics, Volume 42)
by D. C. Rao, Miachael A. Province, Michael A. Province (Editor)
Hardcover - 474 pages Vol 42 (October 2000) Academic Pr; ISBN: 0120176424 ; Dimensions (in inches): 1.27 x 9.27 x 6.20 

Price: US$139.95
Table of contents
Amazon.com customers rating: 

Reviewer: A reader from St. Louis, MO USA 
There has been a lot of development of novel statistical methods in the last decade which has resulted in a better understanding of genetic disorders. There are not many existing books on the subject. This volume is a collection of excellent papers written by some of the renowned experts in the field. The papers range from the basic concepts in genetic epidemiology to applications of some of the most recently developed statistical techniques like CART . The precautions that one needs to take while analyzing genetic data have also been addressed in details. The final chapter by Newton Morton is a treat to  read and provides a great overview of the future directions in the field. Overall the book will be very helpful to all genetic epidemiologists in their research.

Analysis of Human Genetic Linkage
by Jurg Ott
Hardcover - 424 pages 3rd edition (April 1999)  Johns Hopkins Univ Pr; ISBN: 0801861403 ; Dimensions (in inches): 1.45 x 9.26 x 6.32 

Price: US$71.40
Table of contents
Amazon.com customer rating: 

Editorial Reviews:  Book News, Inc. 
An introduction to linkage analysis with emphasis on methodology rather than computer programs. The first chapter presents basic genetic principles in a simple and intuitive manner. Crossing over is introduced and demonstrated in a simple example. Many sections in the first two chapters represent an elementary introduction, and readers without  any statistical knowledge should be able to understand them. For other sections and later chapters, some facility with equations and simple algebra will be beneficial. No introduction to probability calculus is given; however, an  outline of some statistical methods, particularly significance testing, is provided. This third edition reflects changes in the field over the past eight years. The author is affiliated with the Laboratory of Statistical Genetics at the Rockefeller University. -- Copyright © 1999 Book News, Inc., Portland, OR All  rights reserved Book News, Inc.®, Portland, OR 

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Approaches to Gene Mapping in Complex Human Diseases
by Jonathan L. Haines (Editor), Margaret A. Pericak-Vance (Editor)
Hardcover - 434 pages 1st edition (October 15, 1998) Wiley-Liss; ISBN: 0471171956 ; Dimensions (in inches): 1.12 x 9.59 x 6.56 

Price: US$94.50
Table of contents
My rating: 

My comments:
This is a well written book on theoretical and practical aspects on mapping complex disease trait. The ideas are clearly explained. Must read for all beginner!
Genetics and Analysis of Quantitative Traits
by Michael Lynch, Bruce Walsh
Hardcover (December 1997) Sinauer Assoc; ISBN: 0878934812 

Price: US$89.95
Table of contents
Amazon.com customers rating: 

Reviewer: A reader from Lund,Sweden 
An amazing book that really tells you all you need to know about designing and analyzing quantitative genetic experiments. 

Statistical Genomics: Linkage, Mapping, and QTL Analysis
by Ben-Hui Liu
Hardcover - 648 pages (December 29, 1997)  CRC Press; ISBN: 0849331668 ; Dimensions (in inches): 1.51 x 10.28 x 7.32

Price: US$89.95
Table of contents
Amazon.com customers rating: 

Editorial Reviews From Book News, Inc. 
Designed to serve as a textbook for graduate and upper-level undergraduate students, and as a handbook for genomic data analysis. Topics include the screening of genetic markers, linkage analysis and grouping, gene ordering, multilocus models, linkage map construction and merging, the use of population disequilibrium to search for genes, the theory and methods of quantitative trait loci (QTL) mapping, computer tools for genomic map construction and QTL analysis, and resampling techniques and computer simulations. Book News, Inc.®, Portland, OR 

Handbook of Human Genetic Linkage
by Joseph Douglas Terwilliger, Jurg Ott (Contributor)
Paperback - 307 pages (June 1994)  Johns Hopkins Univ Pr; ISBN: 0801848032 ; Dimensions (in inches): 0.86 x 10.94 x 8.52 

Price: $65.00
My rating: 

My comments:
Although this book is a little bit old, but have detailed discussion and guide on commonly used linkage analysis softwares like LINKAGE and HOMOG. A very handy guide for beginner

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last updated: 26 Dec 2003
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